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Descriptor English: TRPA1 Cation Channel
Descriptor Spanish: Canal Catiónico TRPA1
Descriptor canal catiónico TRPA1
Entry term(s) canal TRPA1
miembro 1 de la subfamilia A de canales de cationes de receptores de potencial transitorio
Scope note: Canal catiónico TRP muy conservado, no selectivo, que contiene REPETICIONES DE ANQUIRINA 14-17. Participa en la sensación de frío y en la NOCICEPCIÓN de factores inflamatorios endógenos y de irritantes volátiles. El TPRA1 también es activado por los CANNABINOIDES e interviene en la percepción del sonido por las células ciliadas del oído interno.
Descriptor Portuguese: Canal de Cátion TRPA1
Descriptor French: Membre-1 de la sous-famille A de canaux cationiques à potentiel de récepteur transitoire
Entry term(s): Cation Channel, TRPA1
Channel, TRPA1
Channel, TRPA1 Cation
TRPA1 Channel
Transient Receptor Potential Cation Channel Subfamily A, Member 1
Tree number(s): D12.776.157.530.400.901.250
D12.776.543.585.400.901.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074025
Scope note: A highly conserved, non-selective TRP cation channel that contains 14-17 ANKYRIN REPEATS. It functions in cold sensation and NOCICEPTION of endogenous inflammatory factors and volatile irritants. TRPA1 is also activated by CANNABINOIDS and may play a role in sound perception by hair cells of the inner ear.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Calcium Channels (2003-2017)
Nerve Tissue Proteins (2003-2017)
Transient Receptor Potential Channels (2006-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57082
Unique ID: D000074025
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/02
TRPA1 Cation Channel - Preferred
Concept UI M000625224
Scope note A highly conserved, non-selective TRP cation channel that contains 14-17 ANKYRIN REPEATS. It functions in cold sensation and NOCICEPTION of endogenous inflammatory factors and volatile irritants. TRPA1 is also activated by CANNABINOIDS and may play a role in sound perception by hair cells of the inner ear.
Preferred term TRPA1 Cation Channel
Entry term(s) Cation Channel, TRPA1
Channel, TRPA1
Channel, TRPA1 Cation
TRPA1 Channel
Transient Receptor Potential Cation Channel Subfamily A, Member 1



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