| Descriptor English: | Sodium-Hydrogen Exchanger 3 | ||||||
| Descriptor Spanish: |
Intercambiador 3 de Sodio-Hidrógeno
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| Descriptor Portuguese: | Trocador 3 de Sódio-Hidrogênio | ||||||
| Descriptor French: | Échangeur-3 de sodium-hydrogène | ||||||
| Entry term(s): |
NHE 3 Protein NHE-3 Protein Na(+)-H(+) Exchanger 3 SLC9A3 Protein Sodium Hydrogen Exchanger 3 Solute Carrier Family 9 Member 3 |
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| Tree number(s): |
D12.776.157.530.450.162.775.750 D12.776.157.530.937.703.750 D12.776.543.550.190.775.750 D12.776.543.585.450.162.775.750 D12.776.543.585.937.828.750 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074083 | ||||||
| Scope note: | A sodium-hydrogen antiporter expressed primarily by EPITHELIAL CELLS in the kidneys, it localizes to the apical membrane of the PROXIMAL KIDNEY TUBULE, where it functions in sodium and water reabsorption and possibly calcium homeostasis. It also is expressed in heart, brain, and lung tissues and is resistant to AMILORIDE inhibition. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2018; SODIUM-HYDROGEN EXCHANGER 3 was indexed under SODIUM-HYDROGEN EXCHANGERS 1994-2017 |
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| History Note: | 2018 (1994) |
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| DeCS ID: | 57085 | ||||||
| Unique ID: | D000074083 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/02/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Sodium-Hydrogen Exchanger 3
- Preferred
| Concept UI |
M000625448 |
| Scope note | A sodium-hydrogen antiporter expressed primarily by EPITHELIAL CELLS in the kidneys, it localizes to the apical membrane of the PROXIMAL KIDNEY TUBULE, where it functions in sodium and water reabsorption and possibly calcium homeostasis. It also is expressed in heart, brain, and lung tissues and is resistant to AMILORIDE inhibition. |
| Preferred term | Sodium-Hydrogen Exchanger 3 |
| Entry term(s) |
NHE 3 Protein NHE-3 Protein Na(+)-H(+) Exchanger 3 SLC9A3 Protein Sodium Hydrogen Exchanger 3 Solute Carrier Family 9 Member 3 |
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