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Descriptor English: Organic Cation Transporter 2
Descriptor Spanish: Transportador 2 de Cátion Orgánico
Descriptor transportador 2 de cationes orgánicos
Entry term(s) miembro 2 de la familia 22 de transportadores de solutos
proteína OCT2
proteína SLC22A2
transportador 2 de catión orgánico
Scope note: Transportador de cationes orgánicos que consta de doce dominios transmembranarios y se expresa principalmente en el riñón. Transporta, desde la sangre a los TÚBULOS RENALES, una amplia gama de metabolitos, fármacos y neurotransmisores, tales como DOPAMINA, SEROTONINA, COLINA y CISPLATINO.
Descriptor Portuguese: Transportador 2 de Cátion Orgânico
Descriptor French: Transporteur-2 de cations organiques
Entry term(s): OCT2 Protein
SLC22A2 Protein
Solute Carrier Family 22 Member 2
Tree number(s): D12.776.157.530.450.250.812.625
D12.776.157.530.937.612.625
D12.776.543.585.450.250.812.625
D12.776.543.585.937.701.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075102
Scope note: Organic cation transporter consisting of twelve transmembrane domains and expressed primarily in the kidney. It transports a wide range of metabolites, drugs, and neurotransmitters from the blood to the KIDNEY TUBULES, including DOPAMINE; SEROTONIN; CHOLINE; and CISPLATIN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Carrier Proteins (1996-2017)
Organic Cation Transport Proteins (2002-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57086
Unique ID: D000075102
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/24
Organic Cation Transporter 2 - Preferred
Concept UI M000629237
Scope note Organic cation transporter consisting of twelve transmembrane domains and expressed primarily in the kidney. It transports a wide range of metabolites, drugs, and neurotransmitters from the blood to the KIDNEY TUBULES, including DOPAMINE; SEROTONIN; CHOLINE; and CISPLATIN.
Preferred term Organic Cation Transporter 2
Entry term(s) OCT2 Protein
SLC22A2 Protein
Solute Carrier Family 22 Member 2



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