| Descriptor English: | Solute Carrier Family 22 Member 5 | ||||||
| Descriptor Spanish: |
Miembro 5 de la Familia 22 de Transportadores de Solutos
| ||||||
| Descriptor Portuguese: | Membro 5 da Família 22 de Carreadores de Soluto | ||||||
| Descriptor French: | Membre-5 de la famille-22 de transporteurs de solutés | ||||||
| Entry term(s): |
Carnitine Cotransporter, Sodium-Dependent Carnitine Transporter, High-Affinity High Affinity Carnitine Transporter High-Affinity Carnitine Transporter OCTN2 Protein Organic Cation Carnitine Transporter 2 Organic Cation-Carnitine Transporter 2 SLC22A5 Protein Sodium Dependent Carnitine Cotransporter Sodium-Dependent Carnitine Cotransporter Transporter, High-Affinity Carnitine |
||||||
| Tree number(s): |
D12.776.157.530.450.250.812.750 D12.776.157.530.937.612.750 D12.776.543.585.450.250.812.750 D12.776.543.585.937.701.750 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074058 | ||||||
| Scope note: | A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency. |
||||||
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
||||||
| Previous Indexing: |
Carrier Proteins (1998-2017) Organic Cation Transport Proteins (2004-2017) |
||||||
| Public MeSH Note: | 2018 |
||||||
| History Note: | 2018 |
||||||
| DeCS ID: | 57087 | ||||||
| Unique ID: | D000074058 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/03/31 |
-
-
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
|
Solute Carrier Family 22 Member 5
- Preferred
| Concept UI |
M000625386 |
| Scope note | A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency. |
| Preferred term | Solute Carrier Family 22 Member 5 |
| Entry term(s) |
Carnitine Cotransporter, Sodium-Dependent Carnitine Transporter, High-Affinity High Affinity Carnitine Transporter High-Affinity Carnitine Transporter OCTN2 Protein Organic Cation Carnitine Transporter 2 Organic Cation-Carnitine Transporter 2 SLC22A5 Protein Sodium Dependent Carnitine Cotransporter Sodium-Dependent Carnitine Cotransporter Transporter, High-Affinity Carnitine |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
