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Descriptor English: Peroxisome-Targeting Signal 1 Receptor
Descriptor Spanish: Receptor de la Señal 1 de Direccionamiento al Peroxisoma
Descriptor receptor de la señal 1 de direccionamiento al peroxisoma
Entry term(s) factor 5 de la biogénesis del peroxisoma
peroxina 5
peroxina-5
receptor 1 del peroxisoma
receptor PTS1
receptores PTS1
Scope note: Receptor citoplasmático y peroxina que contiene una serie de REPETICIONES DE TETRATRICOPÉPTIDOS y que se une a la SEÑAL 1 DE DIRECCIONAMIENTO AL PEROXISOMA (tipo SKL). Es esencial para la importación de proteínas a los PEROXISOMAS; las mutaciones del gen PEX5 se asocian a TRASTORNOS PEROXISÓMICOS como el SÍNDROME DE ZELLWEGER.
Descriptor Portuguese: Receptor 1 de Sinal de Orientação para Peroxissomos
Descriptor French: Récepteur de la séquence-1 d'adressage au peroxysome
Entry term(s): PEX5, Peroxin
PTS1 Receptor
PTS1 Receptors
Peroxin 5
Peroxin PEX5
Peroxin-5
Peroxisomal Biogenesis Factor 5
Peroxisome Receptor 1
Peroxisome Targeting Signal 1 Receptor
Receptor, PTS1
Receptors, PTS1
Tree number(s): D12.776.157.635.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074435
Scope note: A cytoplasmic receptor and peroxin that contains a series of TETRATRICOPEPTIDE REPEATS and binds to PEROXISOME TARGETING SIGNAL 1 (SKL-type). It is essential for protein import into PEROXISOMES; mutations in the PEX5 gene are associated with PEROXISOMAL DISORDERS such as ZELLWEGER SYNDROME.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2018; PEROXISOME TARGETING SIGNAL 1 RECEPTOR was indexed under RECEPTORS, CYTOPLASMIC AND NUCLEAR 1996-2017, and under RECEPTORS, CELL SURFACE 1995
History Note: 2018 (1995)
DeCS ID: 57093
Unique ID: D000074435
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2018/10/10
Peroxisome-Targeting Signal 1 Receptor - Preferred
Concept UI M0245711
Scope note A cytoplasmic receptor and peroxin that contains a series of TETRATRICOPEPTIDE REPEATS and binds to PEROXISOME TARGETING SIGNAL 1 (SKL-type). It is essential for protein import into PEROXISOMES; mutations in the PEX5 gene are associated with PEROXISOMAL DISORDERS such as ZELLWEGER SYNDROME.
Preferred term Peroxisome-Targeting Signal 1 Receptor
Entry term(s) PEX5, Peroxin
PTS1 Receptor
PTS1 Receptors
Peroxin 5
Peroxin PEX5
Peroxin-5
Peroxisomal Biogenesis Factor 5
Peroxisome Receptor 1
Peroxisome Targeting Signal 1 Receptor
Receptor, PTS1
Receptors, PTS1



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