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Descriptor English: Peroxisomal Targeting Signal 2 Receptor
Descriptor Spanish: Receptor de la Señal 2 de Direccionamiento al Peroxisoma
Descriptor receptor de la señal 2 de direccionamiento al peroxisoma
Entry term(s) Pex7p
peroxina-7
proteína PEX7
proteína PTS2
receptor PTS2
receptores PTS2
Scope note: Receptor citoplasmático y peroxina que contiene una serie de REPETICIONES WD40 y que se une a la SEÑAL 2 DE DIRECCIONAMIENTO AL PEROXISOMA. Es esencial para la importación de proteínas a los PEROXISOMAS; las mutaciones del gen PEX7 se asocian a TRASTORNOS PEROXISOMALES como la CONDRODISPLASIA PUNCTATA RIZOMÉLICA tipo 1.
Descriptor Portuguese: Receptor 2 de Sinal de Orientação para Peroxissomos
Descriptor French: Récepteur de la séquence-2 d'adressage au peroxysome
Entry term(s): PEX7 Protein
PTS2 Protein
PTS2 Receptor
PTS2 Receptors
Peroxin 7
Peroxin-7
Pex7p
Receptor, PTS2
Receptors, PTS2
Tree number(s): D12.776.157.635.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074437
Scope note: A cytoplasmic receptor and peroxin that contains a series of WD40 REPEATS and binds to PEROXISOME TARGETING SIGNAL 2. It is essential for protein import into PEROXISOMES; mutations in the human PEX7 gene are associated with PEROXISOMAL DISORDERS such as Type 1 CHONDRODYSPLASIA PUNCTATA, RHIZOMELIC.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2018; PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR was indexed under RECEPTORS, CYTOPLASMIC AND NUCLEAR 1995-2017
History Note: 2018 (1995)
DeCS ID: 57092
Unique ID: D000074437
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05
Peroxisomal Targeting Signal 2 Receptor - Preferred
Concept UI M0251192
Scope note A cytoplasmic receptor and peroxin that contains a series of WD40 REPEATS and binds to PEROXISOME TARGETING SIGNAL 2. It is essential for protein import into PEROXISOMES; mutations in the human PEX7 gene are associated with PEROXISOMAL DISORDERS such as Type 1 CHONDRODYSPLASIA PUNCTATA, RHIZOMELIC.
Preferred term Peroxisomal Targeting Signal 2 Receptor
Entry term(s) PEX7 Protein
PTS2 Protein
PTS2 Receptor
PTS2 Receptors
Peroxin 7
Peroxin-7
Pex7p
Receptor, PTS2
Receptors, PTS2



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