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Descriptor English: Peroxisomal Biogenesis Factor 2
Descriptor Spanish: Factor 2 de la Biogénesis del Peroxisoma
Descriptor Portuguese: Fator 2 da Biogênese de Peroxissomos
Descriptor French: Facteur-2 de biogénèse péroxysomale
Entry term(s): PMP35
Peroxin 2
Peroxin-2
Peroxisomal Membrane Protein 35
Peroxisome Assembly Factor 1
Peroxisome Assembly Factor-1
Peroxisome Biogenesis Factor 2
Tree number(s): D12.776.157.635.500
D12.776.543.689
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074428
Scope note: A multi-pass transmembrane protein that contains a C-terminal RING finger domain. It localizes to the PEROXISOME membrane and is essential for peroxisome biogenesis. Mutations in the PEX2 gene are associated with ZELLWEGER SYNDROME and INFANTILE REFSUM DISEASE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 135847-86-8
Public MeSH Note: 2018; see PEROXISOME ASSEMBLY FACTOR-1 1991-2017; PEROXISOMAL BIOGENESIS FACTOR 2 was indexed under MEMBRANE PROTEINS 1991-2017
History Note: 2018 (1991)
Related: RING Finger Domains MeSH
DeCS ID: 57091
Unique ID: D000074428
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05
Peroxisomal Biogenesis Factor 2 - Preferred
Concept UI M0185701
Scope note A multi-pass transmembrane protein that contains a C-terminal RING finger domain. It localizes to the PEROXISOME membrane and is essential for peroxisome biogenesis. Mutations in the PEX2 gene are associated with ZELLWEGER SYNDROME and INFANTILE REFSUM DISEASE.
Preferred term Peroxisomal Biogenesis Factor 2
Entry term(s) PMP35
Peroxin 2
Peroxin-2
Peroxisomal Membrane Protein 35
Peroxisome Assembly Factor 1
Peroxisome Assembly Factor-1
Peroxisome Biogenesis Factor 2



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