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Descriptor English: Gefitinib
Descriptor Spanish: Gefitinib
Descriptor gefitinib
Scope note: Inhibidor selectivo de la tirosina-cinasa del RECEPTOR DEL FACTOR DE CRECIMIENTO EPIDÉRMICO (EGFR) que se usa para el tratamiento del CARCINOMA PULMONAR NO MICROCÍTICO localmente avanzado o metastásico.
Descriptor Portuguese: Gefitinibe
Descriptor French: Géfitinib
Entry term(s): Iressa
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamide
ZD 1839
ZD1839
Tree number(s): D03.633.100.786.469
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077156
Scope note: A selective tyrosine kinase inhibitor for the EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) that is used for the treatment of locally advanced or metastatic NON-SMALL CELL LUNG CANCER.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number: S65743JHBS
Public MeSH Note: 2019; GEFITINIB was indexed under QUINAZOLINES 2001-2018
History Note: 2019 (2001)
DeCS ID: 57526
Unique ID: D000077156
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/01/16
Gefitinib - Preferred
Concept UI M0444984
Scope note A selective tyrosine kinase inhibitor for the EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) that is used for the treatment of locally advanced or metastatic NON-SMALL CELL LUNG CANCER.
Preferred term Gefitinib
Entry term(s) N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamide
Iressa - Narrower
Concept UI M0429113
Preferred term Iressa
ZD1839 - Narrower
Concept UI M0378315
Preferred term ZD1839
Entry term(s) ZD 1839



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