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Descriptor English: Linagliptin
Descriptor Spanish: Linagliptina
Descriptor Portuguese: Linagliptina
Descriptor French: Linagliptine
Entry term(s): (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione
1356, BI
1H-purine-2,6-dione, 8-((3r)-3-amino-1-piperidinyl)-7-(2-butynyl)-3,7-dihydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-
BI 1356
BI-1356
BI1356
Tradjenta
Trajenta
Tree number(s): D03.633.100.759.562
D03.633.100.786.563
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069476
Scope note: A purine and quinazoline derivative that functions as an INCRETIN and DIPEPTIDYL-PEPTIDASE IV INHIBTOR. It is used as a HYPOGLYCEMIC AGENT in the treatment of TYPE II DIABETES MELLITUS.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Hypoglycemic Agents
Incretins
Dipeptidyl-Peptidase IV Inhibitors
Registry Number: 3X29ZEJ4R2
Public MeSH Note: 2016; LINAGLIPTIN was indexed under PURINES and QUINAZOLINES 2011-2015
History Note: 2016 (2011)
Related: Sitagliptin Phosphate MeSH
DeCS ID: 55934
Unique ID: D000069476
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2016/05/31
Linagliptin - Preferred
Concept UI M0554626
Scope note A purine and quinazoline derivative that functions as an INCRETIN and DIPEPTIDYL-PEPTIDASE IV INHIBTOR. It is used as a HYPOGLYCEMIC AGENT in the treatment of TYPE II DIABETES MELLITUS.
Preferred term Linagliptin
Entry term(s) (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione
1H-purine-2,6-dione, 8-((3r)-3-amino-1-piperidinyl)-7-(2-butynyl)-3,7-dihydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-
BI 1356 - Narrower
Concept UI M0554625
Preferred term BI 1356
Entry term(s) 1356, BI
BI-1356
BI1356
Tradjenta - Narrower
Concept UI M0569299
Preferred term Tradjenta
Entry term(s) Trajenta



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