Search
Descriptor English: Decitabine
Descriptor Spanish: Decitabina
Descriptor decitabina
Entry term(s) 2' desoxi 5 azacitidina
2'-desoxi-5-azacitidina
5 aza 2' desoxicitidina
5 azadesoxicitidina
5 desoxiazacitidina
5-aza-2'-desoxicitidina
5-azadC
5-azadesoxicitidina
5-desoxiazacitidina
5AzadC
Dacogen
NSC 127716
NSC-127716
NSC127716
compuesto azadC
mesilato de decitabina
Scope note: Derivado de la azacitidina y antimetabolito antineoplásico. Inhibe la ADN-metiltransferasa para reactivar genes silentes, limitando las METÁSTASIS y la RESISTENCIA A LOS ANTINEOPLÁSICOS. La decitabina se usa en el tratamiento de los SÍNDROMES MIELODISPLÁSICOS y de la LEUCEMIA MIELOIDE AGUDA.
Descriptor Portuguese: Decitabina
Descriptor French: Décitabine
Entry term(s): 2' Deoxy 5 azacytidine
2'-Deoxy-5-azacytidine
5 Aza 2' deoxycytidine
5 Azadeoxycytidine
5 Deoxyazacytidine
5-Aza-2'-deoxycytidine
5-AzadC
5-Azadeoxycytidine
5-Deoxyazacytidine
5AzadC
AzadC Compound
Compound, AzadC
Dacogen
Decitabine Mesylate
Mesylate, Decitabine
NSC 127716
NSC-127716
NSC127716
Tree number(s): D02.145.150.500
D03.383.742.680.245.217.500
D13.570.685.245.217.500
D13.570.800.286.300.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077209
Scope note: An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Enzyme Inhibitors
Registry Number: 776B62CQ27
Public MeSH Note: 2019; DECITABINE was indexed under AZACITIDINE 1981-2018, and under DEOXYCITIDNE 1977-1980
History Note: 2019 (1977)
Related: Cytarabine MeSH
DeCS ID: 57544
Unique ID: D000077209
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/02
Decitabine - Preferred
Concept UI M0062824
Scope note An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.
Preferred term Decitabine
Entry term(s) 2' Deoxy 5 azacytidine
2'-Deoxy-5-azacytidine
5 Aza 2' deoxycytidine
5 Azadeoxycytidine
5-Aza-2'-deoxycytidine
5-AzadC
5-Azadeoxycytidine
5AzadC
AzadC Compound
Compound, AzadC
Dacogen - Narrower
Concept UI M0497730
Preferred term Dacogen
5-Deoxyazacytidine - Related but not broader or narrower
Concept UI M000639779
Preferred term 5-Deoxyazacytidine
Entry term(s) 5 Deoxyazacytidine
NSC 127716 - Narrower
Concept UI M0062821
Preferred term NSC 127716
Entry term(s) NSC-127716
NSC127716
Decitabine Mesylate - Narrower
Concept UI M0515954
Preferred term Decitabine Mesylate
Entry term(s) Mesylate, Decitabine



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey