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Descriptor English: Cytarabine
Descriptor Spanish: Citarabina
Descriptor citarabina
Entry term(s) Ara C
ara-C
arabinofuranosilcitosina
arabinosilcitosina
arabinósido de citosina
aracitidina
aracitina
beta Ara C
beta-Ara C
Scope note: Análogo de nucleósido de pirimidina, que se usa primordialmente en el tratamiento de leucemias, en especial de las leucemia agudas no linfoblásticas. La citarabina es un antimetabolito antineoplásico que inhibe la síntesis de ADN. Sus acciones son específicas para la fase S del ciclo celular. También tiene propiedades antivirales e inmunosupresoras. (Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Descriptor Portuguese: Citarabina
Descriptor French: Cytarabine
Entry term(s): Ara C
Ara-C
Arabinofuranosylcytosine
Arabinoside, Cytosine
Arabinosylcytosine
Aracytidine
Aracytine
Cytarabine Hydrochloride
Cytonal
Cytosar
Cytosar U
Cytosar-U
Cytosine Arabinoside
beta Ara C
beta-Ara C
Tree number(s): D03.383.742.680.245.453
D13.570.065.300
D13.570.685.245.453
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003561
Scope note: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Antiviral Agents
Immunosuppressive Agents
Registry Number: 04079A1RDZ
CAS Type 1 Name: 2(1H)-Pyrimidinone, 4-amino-1-beta-D-arabinofuranosyl-
Public MeSH Note: 1966
History Note: 1966
Related: Decitabine MeSH
DeCS ID: 3578
Unique ID: D003561
NLM Classification: QV 269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/02/28
Cytarabine - Preferred
Concept UI M0005564
Scope note A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Preferred term Cytarabine
Entry term(s) Arabinofuranosylcytosine
Arabinoside, Cytosine
Arabinosylcytosine
Aracytidine
Cytosine Arabinoside
beta-Ara C - Narrower
Concept UI M0369308
Preferred term beta-Ara C
Entry term(s) beta Ara C
Cytarabine Hydrochloride - Narrower
Concept UI M0005565
Preferred term Cytarabine Hydrochloride
Cytosar - Narrower
Concept UI M0005566
Preferred term Cytosar
Entry term(s) Cytosar U
Cytosar-U
Ara-C - Narrower
Concept UI M0369310
Preferred term Ara-C
Entry term(s) Ara C
Aracytine - Narrower
Concept UI M0369309
Preferred term Aracytine
Cytonal - Narrower
Concept UI M0372750
Preferred term Cytonal



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