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Descriptor English: Vorinostat
Descriptor Spanish: Vorinostat
Descriptor Portuguese: Vorinostat
Descriptor French: Vorinostat
Entry term(s): 18F Suberoylanilide Hydroxamic Acid
18F-SAHA
18F-Suberoylanilide Hydroxamic Acid
M344
MK 0683
MK-0683
MK0683
N Hydroxy N' phenyloctanediamide
N-Hydroxy-N'-phenyloctanediamide
N1 Hydroxy N8 phenyloctanediamide
N1-Hydroxy-N8-phenyloctanediamide
NHNPODA
Suberanilohydroxamic Acid
Suberoyl Anilide Hydroxamic Acid
Suberoylanilide Hydroxamic Acid
Zolinza
Tree number(s): D02.065.199.960
D02.092.146.113.960
D02.092.570.394.690
D02.241.511.372.690
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077337
Scope note: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Histone Deacetylase Inhibitors
Registry Number: 58IFB293JI
Public MeSH Note: 2019; VORINOSTAT was indexed under HYDROXAMIC ACIDS 1998-2018
History Note: 2019 (1998)
DeCS ID: 57621
Unique ID: D000077337
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Vorinostat - Preferred
Concept UI M0288128
Scope note A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
Preferred term Vorinostat
Entry term(s) N Hydroxy N' phenyloctanediamide
N-Hydroxy-N'-phenyloctanediamide
N1 Hydroxy N8 phenyloctanediamide
N1-Hydroxy-N8-phenyloctanediamide
NHNPODA
Suberanilohydroxamic Acid
Suberoyl Anilide Hydroxamic Acid
Suberoylanilide Hydroxamic Acid
M344 - Narrower
Concept UI M0521832
Preferred term M344
MK-0683 - Narrower
Concept UI M000640602
Preferred term MK-0683
Entry term(s) MK 0683
MK0683
18F-SAHA - Narrower
Concept UI M0561702
Preferred term 18F-SAHA
Entry term(s) 18F Suberoylanilide Hydroxamic Acid
18F-Suberoylanilide Hydroxamic Acid
Zolinza - Narrower
Concept UI M0501938
Preferred term Zolinza



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