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Descriptor English: Irbesartan
Descriptor Spanish: Irbesartán
Descriptor Portuguese: Irbesartana
Descriptor French: Irbésartan
Entry term(s): 2-N-Butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one
Aprovel
Avapro
BMS 186295
BMS-186295
Karvea
SR 47436
SR-47436
SR47436
Tree number(s): D02.455.426.559.389.185.413
D02.455.426.779.431
D03.383.129.617.351
D04.711.431
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077405
Scope note: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Angiotensin II Type 1 Receptor Blockers
Registry Number: J0E2756Z7N
CAS Type 1 Name: 1,3-Diazaspiro(4.4)non-1-en-4-one, 2-butyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-
Public MeSH Note: 2019; IRBESARTAN was indexed under BIPHENYL COMPOUNDS and TETRAZOLES 1993-2018
History Note: 2019 (1993)
DeCS ID: 57633
Unique ID: D000077405
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Irbesartan - Preferred
Concept UI M0216909
Scope note A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
Preferred term Irbesartan
Avapro - Narrower
Concept UI M0397886
Preferred term Avapro
Karvea - Narrower
Concept UI M000640708
Preferred term Karvea
2-N-Butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one - Related but not broader or narrower
Concept UI M000640706
Preferred term 2-N-Butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one
Aprovel - Narrower
Concept UI M000640707
Preferred term Aprovel
SR 47436 - Narrower
Concept UI M0216907
Preferred term SR 47436
Entry term(s) SR-47436
SR47436
BMS 186295 - Narrower
Concept UI M0216905
Preferred term BMS 186295
Entry term(s) BMS-186295



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