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Descriptor English: Cilostazol
Descriptor Spanish: Cilostazol
Descriptor Portuguese: Cilostazol
Descriptor French: Cilostazol
Entry term(s): 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone
OPC 13013
OPC-13013
Pletal
Tree number(s): D03.383.129.617.293
D03.633.100.810.069
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077407
Scope note: A quinoline and tetrazole derivative that acts as a phosphodiesterase type 3 inhibitor, with anti-platelet and vasodilating activity. It is used in the treatment of PERIPHERAL VASCULAR DISEASES; ISCHEMIC HEART DISEASE; and in the prevention of stroke.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Bronchodilator Agents
Fibrinolytic Agents
Platelet Aggregation Inhibitors
Vasodilator Agents
Neuroprotective Agents
Phosphodiesterase 3 Inhibitors
Registry Number: N7Z035406B
CAS Type 1 Name: 2(1H)-Quinolinone, 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-
Public MeSH Note: 2019; CILOSTAZOL was indexed under TETRAZOLES 1985-2018
History Note: 2019 (1985)
DeCS ID: 57635
Unique ID: D000077407
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Cilostazol - Preferred
Concept UI M0132637
Scope note A quinoline and tetrazole derivative that acts as a phosphodiesterase type 3 inhibitor, with anti-platelet and vasodilating activity. It is used in the treatment of PERIPHERAL VASCULAR DISEASES; ISCHEMIC HEART DISEASE; and in the prevention of stroke.
Preferred term Cilostazol
Entry term(s) 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone
OPC 13013 - Narrower
Concept UI M0132635
Preferred term OPC 13013
Entry term(s) OPC-13013
Pletal - Narrower
Concept UI M0399069
Preferred term Pletal



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