Descriptor in English: | Aprepitant |
Descriptor in Spanish: | Aprepitant |
Descriptor in Portuguese: | Aprepitanto |
Descriptor in French: | Aprépitant |
Entry term(s): |
(1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methylmorpholine (2R)-(1R)-3,5-bis(Trifluoromethylphenyl)ethoxy)-(3S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazole)methyl-morpholine Emend L 754,030 L 754030 L-754,030 L-754030 L754,030 L754030 MK 0517 MK 0869 MK 869 MK-0517 MK-0869 MK-869 MK0517 MK0869 MK869 |
Tree number(s): |
D03.383.533.640.125 |
Scope note: | A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING. |
Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
History Note: | 2019 (1998) |
DeCS UI: | 57711 |
Descriptor UI: | D000077608 |
Date Established: | 2019/01/01 |
Date of Entry: | 2018/07/09 |
Revision Date: | 2018/04/09 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
|
Aprepitant
- Preferred
MK 869
- Narrower
(2R)-(1R)-3,5-bis(Trifluoromethylphenyl)ethoxy)-(3S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazole)methyl-morpholine
- Related but not broader or narrower
MK 0517
- Narrower
(1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methylmorpholine
- Narrower
Emend
- Narrower
L 754030
- Narrower
Concept UI |
M0447596 |
Scope note | A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING. |
Preferred term | Aprepitant |
Concept UI |
M0295395 |
Preferred term | MK 869 |
Entry term(s) |
MK 0869 MK-0869 MK-869 MK0869 MK869 |
Concept UI |
M000641045 |
Preferred term | (2R)-(1R)-3,5-bis(Trifluoromethylphenyl)ethoxy)-(3S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazole)methyl-morpholine |
Concept UI |
M0529252 |
Preferred term | MK 0517 |
Entry term(s) |
MK-0517 MK0517 |
Concept UI |
M0297559 |
Preferred term | (1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methylmorpholine |
Concept UI |
M0447597 |
Preferred term | Emend |
Concept UI |
M0297563 |
Preferred term | L 754030 |
Entry term(s) |
L 754,030 L-754,030 L-754030 L754,030 L754030 |
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