| Descriptor English: | Axitinib | ||||||
| Descriptor Spanish: |
Axitinib
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| Descriptor Portuguese: | Axitinibe | ||||||
| Descriptor French: | Axitinib | ||||||
| Entry term(s): |
AG 013736 AG-013736 AG013736 Inlyta |
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| Tree number(s): |
D02.065.277.051 D02.241.223.100.100.115 D02.455.426.559.389.127.085.093 D03.383.129.539.487.065 D03.633.100.449.065 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000077784 | ||||||
| Scope note: | A benzamide and indazole derivative that acts as a TYROSINE KINASE inhibitor of the VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR. It is used in the treatment of advanced RENAL CELL CARCINOMA. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Antineoplastic Agents Antineoplásicos Antineoplásicos Antinéoplasiques antineoplásicos Protein Kinase Inhibitors Inhibidores de Proteínas Quinasas Inibidores de Proteínas Quinases Inhibiteurs de protéines kinases inhibidores de proteínas cinasas |
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| Registry Number: | C9LVQ0YUXG | ||||||
| CAS Type 1 Name: | Benzamide, N-methyl-2-((3-((E)-2-(2-pyridinyl)ethenyl)-1H-indazol-6-yl)thio)- | ||||||
| Public MeSH Note: | 2019; AXITINIB was indexed under IMIDAZOLES and INDAZOLES 2005-2018 |
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| History Note: | 2019 (2005) |
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| DeCS ID: | 57757 | ||||||
| Unique ID: | D000077784 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2019/01/01 | ||||||
| Date of Entry: | 2018/07/09 | ||||||
| Revision Date: | 2018/05/21 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Axitinib
- Preferred
AG 013736
- Narrower
Inlyta
- Narrower
| Concept UI |
M0489638 |
| Scope note | A benzamide and indazole derivative that acts as a TYROSINE KINASE inhibitor of the VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR. It is used in the treatment of advanced RENAL CELL CARCINOMA. |
| Preferred term | Axitinib |
| Concept UI |
M0496201 |
| Preferred term | AG 013736 |
| Entry term(s) |
AG-013736 AG013736 |
| Concept UI |
M0578346 |
| Preferred term | Inlyta |
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