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Descriptor English: Atrasentan
Descriptor Spanish: Atrasentán
Descriptor atrasentán
Entry term(s) (11C)ABT-627
A 127722
A 127722.5
A 147627
A-127722
A-127722.5
A-147627
A127722
A127722.5
A147627
ABT 627
ABT-627
ABT627
Xinlay
clorhidrato de atrasentán
hidrocloruro de atrasentán
ácido 2-(4-metoxifenil)-4-(1,3-benzodioxol-5-il)-1-(((dibutilamino)carbonil)metil)pirrolidin-3-carboxílico
Scope note: Derivado pirrolidínico y benzodioxólico que actúa como antagonista del RECEPTOR DE ENDOTELINA A. Tiene potencial terapéutico como antineoplásico y para el tratamiento de las NEFROPATÍAS DIABÉTICAS.
Descriptor Portuguese: Atrasentana
Descriptor French: Atrasentan
Entry term(s): A-127722
A-127722.5
A-147627
A127722
A147627
ABT-627
ABT627
Tree number(s): D03.383.246.118.300
D03.383.773.079
D03.633.100.115.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077868
Scope note: A pyrrolidine and benzodioxole derivative that acts a RECEPTOR, ENDOTHELIN A antagonist. It has therapeutic potential as an antineoplastic agent and for the treatment of DIABETIC NEPHROPATHIES.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents
Endothelin A Receptor Antagonists
Registry Number: V6D7VK2215
CAS Type 1 Name: 3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)-, (2R,3R,4S)-
DeCS ID: 57771
Unique ID: D000077868
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/21
Atrasentan - Preferred
Concept UI M0393223
Preferred term Atrasentan
A-127722 - Narrower
Concept UI M0259089
Preferred term A-127722
Entry term(s) A-127722.5
A127722
A-147627 - Narrower
Concept UI M0259083
Preferred term A-147627
Entry term(s) A147627
ABT-627 - Narrower
Concept UI M0259087
Preferred term ABT-627
Entry term(s) ABT627



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