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Descriptor English: G(M2) Ganglioside
Descriptor Spanish: Gangliósido G(M2)
Descriptor gangliósido G(M2)
Entry term(s) gangliósido GM2
gangliósido de la enfermedad de Tay-Sachs
Scope note: Glicoesfingolípido que se acumula cuando existe una deficiencia de hexosaminidasa A o B (BETA-N-ACETILHEXOSAMINIDASAS), o proteína activadora de GM2, causando GANGLIOSIDOSIS, trastornos metabólicos hereditarios entre los que se encuentran la ENFERMEDAD DE TAY-SACHS y la ENFERMEDAD DE SANDHOFF.
Descriptor Portuguese: Gangliosídeo G(M2)
Descriptor French: Ganglioside GM2
Entry term(s): GM2 Ganglioside
GM2, Ganglioside
Ganglioside GM2
Ganglioside, GM2
Ganglioside, Tay-Sachs Disease
Tay Sachs Disease Ganglioside
Tay-Sachs Disease Ganglioside
Tree number(s): D09.400.410.420.025.475.400
D10.390.470.025.475.400
D10.570.877.360.025.475.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005678
Scope note: A glycosphingolipid that accumulates due to a deficiency of hexosaminidase A or B (BETA-N-ACETYLHEXOSAMINIDASES), or GM2 activator protein, resulting in GANGLIOSIDOSES, heredity metabolic disorders that include TAY-SACHS DISEASE and SANDHOFF DISEASE.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 19600-01-2
CAS Type 1 Name: Ganglioside GM2
Previous Indexing: Gangliosides (1974)
Public MeSH Note: 91; was see under GANGLIOSIDES 1975-90
History Note: 91(75); was see under GANGLIOSIDES 1975-90
Entry Version: GM2 GANGLIOSIDE
Related: Sandhoff Disease MeSH
Tay-Sachs Disease MeSH
DeCS ID: 5816
Unique ID: D005678
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2019/03/22
G(M2) Ganglioside - Preferred
Concept UI M0008925
Scope note A glycosphingolipid that accumulates due to a deficiency of hexosaminidase A or B (BETA-N-ACETYLHEXOSAMINIDASES), or GM2 activator protein, resulting in GANGLIOSIDOSES, heredity metabolic disorders that include TAY-SACHS DISEASE and SANDHOFF DISEASE.
Preferred term G(M2) Ganglioside
Entry term(s) GM2 Ganglioside
GM2, Ganglioside
Ganglioside GM2
Ganglioside, GM2
Ganglioside, Tay-Sachs Disease
Tay Sachs Disease Ganglioside
Tay-Sachs Disease Ganglioside



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