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Descriptor English: G(M3) Ganglioside
Descriptor Spanish: Gangliósido G(M3)
Descriptor gangliósido G(M3)
Entry term(s) hematósido
sialil lactosil ceramida
Scope note: gangliósido presente en cantidad anómalamente elevada en el cerebro e hígado cuando existe una deficiencia de una enzima biosintética, G(M3):UDP-N-acetilgalactosaminiltransferasa. La deficiencia de esta enzima impide la formación del gangliósido G(M2) a partir del gangliósido G(M3), siendo esta la causa de una esfingolipidosis anabólica.
Descriptor Portuguese: Gangliosídeo G(M3)
Descriptor French: Ganglioside GM3
Entry term(s): GM3, Ganglioside
Ganglioside GM3
Hematoside
II3NeuAcLacCer
Lactosylceramide, Sialyl
Sialyl Lactosylceramide
Sialyllactosylceramide
Tree number(s): D09.400.410.420.025.475.510
D10.390.470.025.475.510
D10.570.877.360.025.475.510
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005679
Scope note: A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.
Annotation: G(M3) gangliosidosis: coord NIM with GANGLIOSIDOSIS (IM)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Gangliosides (1966-1976)
Public MeSH Note: 91; was see under GANGLIOSIDES 1977-90
History Note: 91(77); was see under GANGLIOSIDES 1977-90
DeCS ID: 5817
Unique ID: D005679
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/05/19
Revision Date: 2004/07/07
G(M3) Ganglioside - Preferred
Concept UI M0008926
Scope note A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.
Preferred term G(M3) Ganglioside
Entry term(s) GM3, Ganglioside
Ganglioside GM3
Hematoside
II3NeuAcLacCer
Lactosylceramide, Sialyl
Sialyl Lactosylceramide
Sialyllactosylceramide



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