Search
Descriptor English: Protein-Arginine Deiminase Type 4
Descriptor Spanish: Arginina Deiminasa Proteína-Tipo 4
Descriptor desiminasa de la arginina proteínica de tipo 4
Entry term(s) desiminasa de la arginina proteínica 4
desiminasa de la arginina proteínica de tipo IV
enzima PAD V
peptidil-arginina-desiminasa de tipo 4
peptidil-arginina-desiminasa de tipo IV
peptidilarginina-desiminasa IV
peptidilarginina-desiminasa V
peptidilarginina-desiminasa de tipo 4
peptidilarginina-desiminasa de tipo IV
proteína PADI4
proteína PADI5
Scope note: Enzima de modificación de histonas que convierte la ARGININA y la monometil-arginina en CITRULINA. Es una de varias isoenzimas de la desiminasa de la arginina proteínica. Es un regulador génico implicado en la APOPTOSIS y en la DIFERENCIACIÓN CELULAR y una posible diana terapéutica para el tratamiento de diversas enfermedades.
Descriptor Portuguese: Proteína-Arginina Desiminase do Tipo 4
Descriptor French: Protein-arginine deiminase Type 4
Entry term(s): PAD V Enzyme
PADI4 Protein
PADI5 Protein
Peptidyl Arginine Deiminase Type 4
Peptidyl Arginine Deiminase Type IV
Peptidylarginine Deiminase IV
Peptidylarginine Deiminase Type 4
Peptidylarginine Deiminase Type IV
Peptidylarginine Deiminase V
Protein Arginine Deiminase 4
Protein Arginine Deiminase Type 4
Protein Arginine Deiminase Type IV
Protein-Arginine Deiminase Type IV
Tree number(s): D08.811.277.721.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000080002
Scope note: A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.5.3.15
Public MeSH Note: 2020; for PEPTIDYLARGININE DEIMINASE TYPE IV use PROTEIN-ARGININE DEIMINASES 2004-2019; for PEPTIDYLARGININE DEIMINASE V use PROTEIN-ARGININE DEIMINASES 2003-2019
History Note: 2020 (2004)
Related: Citrullination MeSH
DeCS ID: 59205
Unique ID: D000080002
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/05/30
Protein-Arginine Deiminase Type 4 - Preferred
Concept UI M0303511
Scope note A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases.
Preferred term Protein-Arginine Deiminase Type 4
Entry term(s) PAD V Enzyme
PADI4 Protein
PADI5 Protein
Peptidyl Arginine Deiminase Type 4
Peptidyl Arginine Deiminase Type IV
Peptidylarginine Deiminase IV
Peptidylarginine Deiminase Type 4
Peptidylarginine Deiminase Type IV
Peptidylarginine Deiminase V
Protein Arginine Deiminase 4
Protein Arginine Deiminase Type 4
Protein Arginine Deiminase Type IV
Protein-Arginine Deiminase Type IV



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey