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Descriptor English: Macroautophagy
Descriptor Spanish: Macroautofagia
Descriptor macroautofagia
Entry term(s) agrefagia
autofagia selectiva mediada por chaperonas
lisofagia
macro-autofagia
pexofagia
proteafagia
xenofagia
Scope note: Segregación de grandes porciones de citoplasma, incluidos ORGÁNULOS y AGREGADOS PROTEICOS, en AUTOFAGOSOMAS y degradación lisosómica tras la fusión con LISOSOMAS.
Descriptor Portuguese: Macroautofagia
Descriptor French: Without translation
Entry term(s): Aggrephagy
Autophagies, Chaperone-Assisted-Selective
Autophagy, Chaperone-Assisted-Selective
Chaperone Assisted Selective Autophagy
Chaperone-Assisted-Selective Autophagy
Lysophagy
Macro Autophagy
Macro-Autophagy
Pexophagy
Proteaphagy
Xenophagy
Tree number(s): G04.011.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000080550
Scope note: The segregation of large parts of the cytoplasm, including ORGANELLES and PROTEIN AGGREGATES, into AUTOPHAGOSOMES and lysosomal degradation after fusion with LYSOSOMES.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Autophagy (1991-2019)
Public MeSH Note: 2020; see AUTOPHAGY 2017-2019
History Note: 2020; use AUTOPHAGY 2017-2019
DeCS ID: 59280
Unique ID: D000080550
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/07/05
Macroautophagy - Preferred
Concept UI M000647960
Scope note The segregation of large parts of the cytoplasm, including ORGANELLES and PROTEIN AGGREGATES, into AUTOPHAGOSOMES and lysosomal degradation after fusion with LYSOSOMES.
Preferred term Macroautophagy
Entry term(s) Macro Autophagy
Macro-Autophagy
Pexophagy - Narrower
Concept UI M000648265
Scope note Macroautophagic degradation of PEROXISOMES. In yeast peroxisomes are degraded via a microautophagic process known as MICROPEXOPHAGY.
Preferred term Pexophagy
Xenophagy - Narrower
Concept UI M000648266
Scope note Autophagic degradation of microorganisms in the CYTOPLASM.
Preferred term Xenophagy
Chaperone-Assisted-Selective Autophagy - Broader
Concept UI M000648271
Scope note A selective type of macroautophagy in which PROTEIN AGGREGATES that are bound to chaperone HSPPA8 and other co-chaperones are taken in for lysosomal degradation by invagination. It is distinguished from CHAPERONE-MEDIATED AUTOPHAGY.
Preferred term Chaperone-Assisted-Selective Autophagy
Entry term(s) Autophagies, Chaperone-Assisted-Selective
Autophagy, Chaperone-Assisted-Selective
Chaperone Assisted Selective Autophagy
Lysophagy - Narrower
Concept UI M000648268
Scope note Autophagic degradation of damaged LYSOSOMES.
Preferred term Lysophagy
Aggrephagy - Narrower
Concept UI M000648270
Preferred term Aggrephagy
Proteaphagy - Narrower
Concept UI M000648267
Scope note Macroautophagic degradation of PROTEASOMES.
Preferred term Proteaphagy



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