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Descriptor English: Immune Checkpoint Inhibitors
Descriptor Spanish: Inhibidores de Puntos de Control Inmunológico
Descriptor Portuguese: Inibidores de Checkpoint Imunológico
Descriptor French: Without translation
Entry term(s): Blockade, PD-1-PD-L1
CTLA 4 Inhibitor
CTLA 4 Inhibitors
CTLA-4 Inhibitor
CTLA-4 Inhibitors
Checkpoint Blockade, Immune
Checkpoint Blockers, Immune
Checkpoint Inhibition, Immune
Checkpoint Inhibitor, Immune
Checkpoint Inhibitors, Immune
Cytotoxic T Lymphocyte Associated Protein 4 Inhibitor
Cytotoxic T Lymphocyte Associated Protein 4 Inhibitors
Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitor
Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitors
Immune Checkpoint Blockade
Immune Checkpoint Blockers
Immune Checkpoint Inhibition
Immune Checkpoint Inhibitor
Inhibitor, PD-1
PD 1 Inhibitor
PD 1 Inhibitors
PD 1 PD L1 Blockade
PD L1 Inhibitor
PD L1 Inhibitors
PD-1 Inhibitor
PD-1 Inhibitors
PD-1-PD-L1 Blockade
PD-L1 Inhibitor
PD-L1 Inhibitors
Programmed Cell Death Protein 1 Inhibitor
Programmed Cell Death Protein 1 Inhibitors
Programmed Death Ligand 1 Inhibitors
Programmed Death-Ligand 1 Inhibitors
Tree number(s): D27.505.519.507
D27.505.954.248.487
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000082082
Scope note: Drugs that block negative regulator IMMUNE CHECKPOINT proteins (e.g., PD-1 RECEPTOR and CTLA-4 ANTIGEN) thereby increasing suppressed immune activation in immunotherapies.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Antineoplastic Agents (2017-2020)
Public MeSH Note: 2021
History Note: 2021
DeCS ID: 59322
Unique ID: D000082082
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2021/01/01
Date of Entry: 2020/07/07
Revision Date: 2020/05/27
Immune Checkpoint Inhibitors - Preferred
Concept UI M000675754
Scope note Drugs that block negative regulator IMMUNE CHECKPOINT proteins (e.g., PD-1 RECEPTOR and CTLA-4 ANTIGEN) thereby increasing suppressed immune activation in immunotherapies.
Preferred term Immune Checkpoint Inhibitors
Entry term(s) Checkpoint Blockers, Immune
Checkpoint Inhibitor, Immune
Checkpoint Inhibitors, Immune
Immune Checkpoint Blockers
Immune Checkpoint Inhibitor
Immune Checkpoint Blockade - Broader
Concept UI M000677227
Preferred term Immune Checkpoint Blockade
Entry term(s) Checkpoint Blockade, Immune
Checkpoint Inhibition, Immune
Immune Checkpoint Inhibition
PD-L1 Inhibitors - Narrower
Concept UI M000678017
Preferred term PD-L1 Inhibitors
Entry term(s) PD L1 Inhibitor
PD L1 Inhibitors
PD-L1 Inhibitor
Programmed Death Ligand 1 Inhibitors
Programmed Death-Ligand 1 Inhibitors
CTLA-4 Inhibitors - Narrower
Concept UI M000675755
Preferred term CTLA-4 Inhibitors
Entry term(s) CTLA 4 Inhibitor
CTLA 4 Inhibitors
CTLA-4 Inhibitor
Cytotoxic T Lymphocyte Associated Protein 4 Inhibitor
Cytotoxic T Lymphocyte Associated Protein 4 Inhibitors
Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitor
Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitors
PD-1 Inhibitors - Narrower
Concept UI M000675756
Preferred term PD-1 Inhibitors
Entry term(s) Inhibitor, PD-1
PD 1 Inhibitor
PD 1 Inhibitors
PD-1 Inhibitor
Programmed Cell Death Protein 1 Inhibitor
Programmed Cell Death Protein 1 Inhibitors
PD-1-PD-L1 Blockade - Narrower
Concept UI M000678018
Preferred term PD-1-PD-L1 Blockade
Entry term(s) Blockade, PD-1-PD-L1
PD 1 PD L1 Blockade



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