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Descriptor English: Mast Cell Activation Disorders
Descriptor Spanish: Trastornos de la Activación de los Mastocitos
Descriptor trastornos por activación de los mastocitos
Entry term(s) enfermedad de los mastocitos
enfermedad mastocitaria
enfermedad mastocítica
enfermedad por activación de los mastocitos
síndrome de activación monoclonal de los mastocitos
trastornos por activación primaria de los mastocitos
trastornos por proliferación clonal de los mastocitos
Scope note: Espectro de trastornos primarios, secundarios e idiopáticos en los que intervienen los MASTOCITOS y que se caracterizan por una liberación aberrante de mediadores mastocíticos que causan síntomas inflamatorios y alérgicos múltiples y variables. Estos trastornos se asocian a diversas mutaciones en el receptor tirosina-cinasa KIT (PROTEÍNAS PROTOONCOGÉNICAS C-KIT) y en otros genes, afecciones subyacentes y respuestas a desencadenantes alérgicos o no alérgicos de la estimulación y la desgranulación de los mastocitos, tales como anestésicos locales, antibióticos lactámicos, relajantes musculares, alimentos específicos, toxinas ambientales y situaciones físicas tales como la vibración, el frío, la presión y el estrés.
Descriptor Portuguese: Transtornos da Ativação de Mastócitos
Descriptor French: Troubles de l'activation mastocytaire
Entry term(s): Clonal Mast Cell Proliferation Disorders
Mast Cell Disease
Mast Cell Diseases
Mast-Cell Disease
Mast-Cell Diseases
Monoclonal Mast Cell Activation Syndrome
Primary Mast Cell Activation Disorders
Tree number(s): C20.762
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000090362
Scope note: A spectrum of primary, secondary, and idiopathic disorders involving MAST CELLS and characterized by an aberrant release of mast cell mediators which result in multiple and variable inflammatory and allergic symptoms. These disorders are associated with various mutations in tyrosine kinase KIT (PROTO-ONCOGENE PROTEINS C-KIT) and other genes, underlying conditions, and responses to allergic or non-allergic triggers of mast cell stimulation and degranulation such as local anesthetics, lactam antibiotics, muscle relaxants, specific foods, environmental toxins, physical conditions such as vibration, cold, pressure, and stress.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Public MeSH Note: 2022; for MAST CELL ACTIVATION DISEASE see MASTOCYTOSIS 2018-2021
History Note: 2022; for MAST CELL ACTIVATION DISEASE use MASTOCYTOSIS 2018-2021
DeCS ID: 59796
Unique ID: D000090362
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/07/07
Mast Cell Activation Disorders - Preferred
Concept UI M000738446
Scope note A spectrum of primary, secondary, and idiopathic disorders involving MAST CELLS and characterized by an aberrant release of mast cell mediators which result in multiple and variable inflammatory and allergic symptoms. These disorders are associated with various mutations in tyrosine kinase KIT (PROTO-ONCOGENE PROTEINS C-KIT) and other genes, underlying conditions, and responses to allergic or non-allergic triggers of mast cell stimulation and degranulation such as local anesthetics, lactam antibiotics, muscle relaxants, specific foods, environmental toxins, physical conditions such as vibration, cold, pressure, and stress.
Preferred term Mast Cell Activation Disorders
Entry term(s) Mast Cell Disease
Mast Cell Diseases
Mast-Cell Disease
Mast-Cell Diseases
Primary Mast Cell Activation Disorders - Narrower
Concept UI M000746185
Preferred term Primary Mast Cell Activation Disorders
Entry term(s) Clonal Mast Cell Proliferation Disorders
Monoclonal Mast Cell Activation Syndrome - Narrower
Concept UI M000746285
Preferred term Monoclonal Mast Cell Activation Syndrome



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