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Descriptor English: Glomerulonephritis, Membranoproliferative
Descriptor Spanish: Glomerulonefritis Membranoproliferativa
Descriptor glomerulonefritis membranoproliferativa
Entry term(s) GNMP
MPGN
glomerulonefritis membranoproliferativa (GNMP)
glomerulonefritis mesangiocapilar
glomerulopatía asociada al factor 3 del complemento
glomerulopatía asociada al factor 3 del complemento (GC3)
glomerulopatías asociadas al factor 3 del complemento
Scope note: Glomerulonefritis crónica que se caracteriza histológicamente por proliferación de las células mesangiales, aumento de la matriz mesangial y engrosamiento de las paredes de los capilares del glomérulo. Se dice en ocasiones que el engrosamiento de las paredes es consecuencia de la interposición de citoplasma mesangial o de la matriz entre la membrana basal y el endotelio de la pared capilar. Con frecuencia se divide en los tipos I y II, y algunas veces III. La patogenia no se conoce bien, pero se piensa que en algunos tipos interviene el sistema inmunitario, y en particular se ha implicado al sistema del complemento.
Descriptor Portuguese: Glomerulonefrite Membranoproliferativa
Descriptor French: Glomérulonéphrite membranoproliférative
Entry term(s): C3G Complement 3 Glomerulopathy
Complement 3 Glomerulopathies
Complement 3 Glomerulopathy
DDD MPGNII
Dense Deposit Disease
Glomerulonephritides, Hypocomplementemic
Glomerulonephritides, Membranoproliferative
Glomerulonephritides, Mesangiocapillary
Glomerulonephritis, Hypocomplementemic
Glomerulonephritis, Mesangiocapillary
Glomerulopathies, Complement 3
Glomerulopathy, Complement 3
Hypocomplementemic Glomerulonephritides
Hypocomplementemic Glomerulonephritis
MPGN Membranoproliferative Glomerulonephritis
MPGNII
Membranoproliferative Glomerulonephritides
Membranoproliferative Glomerulonephritis
Membranoproliferative Glomerulonephritis Type II
Membranoproliferative Glomerulonephritis, Subendothelial
Membranoproliferative Glomerulonephritis, Type I
Membranoproliferative Glomerulonephritis, Type II
Membranoproliferative Glomerulonephritis, Type III
Mesangiocapillary Glomerulonephritides
Mesangiocapillary Glomerulonephritis
Mesangiocapillary Glomerulonephritis, Type I
Mesangiocapillary Glomerulonephritis, Type II
Subendothelial Membranoproliferative Glomerulonephritis
Type II MPGN
Tree number(s): C12.050.351.968.419.570.363.615
C12.200.777.419.570.363.615
C12.950.419.570.363.615
C20.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015432
Scope note: Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.
Annotation: do not confuse with GLOMERULONEPHRITIS, MEMBRANOUS; do not make diagnoses: use the term used by the author
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Glomerulonephritis (1969-1988)
Public MeSH Note: 89
History Note: 89
DeCS ID: 23655
Unique ID: D015432
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/06/08
Revision Date: 2022/07/08
Glomerulonephritis, Membranoproliferative - Preferred
Concept UI M0023780
Scope note Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.
Preferred term Glomerulonephritis, Membranoproliferative
Entry term(s) Glomerulonephritides, Hypocomplementemic
Glomerulonephritides, Membranoproliferative
Glomerulonephritides, Mesangiocapillary
Glomerulonephritis, Hypocomplementemic
Glomerulonephritis, Mesangiocapillary
Hypocomplementemic Glomerulonephritides
Hypocomplementemic Glomerulonephritis
MPGN Membranoproliferative Glomerulonephritis
Membranoproliferative Glomerulonephritides
Membranoproliferative Glomerulonephritis
Mesangiocapillary Glomerulonephritides
Mesangiocapillary Glomerulonephritis
Membranoproliferative Glomerulonephritis, Type III - Narrower
Concept UI M0490967
Scope note A type of mesangiocapillary glomerulonephritis that is characterized by subepithelial immune deposit and may be a variant of type I.
Preferred term Membranoproliferative Glomerulonephritis, Type III
Membranoproliferative Glomerulonephritis, Type I - Narrower
Concept UI M0490965
Scope note A type of mesangiocapillary glomerulonephritis that is characterized by immune deposits on the endothelial side of the GLOMERULAR BASEMENT MEMBRANE leading to splitting and reduplication of the basement membrane.
Preferred term Membranoproliferative Glomerulonephritis, Type I
Entry term(s) Membranoproliferative Glomerulonephritis, Subendothelial
Mesangiocapillary Glomerulonephritis, Type I
Subendothelial Membranoproliferative Glomerulonephritis
Membranoproliferative Glomerulonephritis, Type II - Narrower
Concept UI M0490966
Scope note A type of mesangiocapillary glomerulonephritis that is characterized by the dark bands of electron-dense deposits in the GLOMERULAR BASEMENT MEMBRANE caused by autoantibodies against ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb).
Preferred term Membranoproliferative Glomerulonephritis, Type II
Entry term(s) DDD MPGNII
Dense Deposit Disease
MPGNII
Membranoproliferative Glomerulonephritis Type II
Mesangiocapillary Glomerulonephritis, Type II
Type II MPGN
Complement 3 Glomerulopathies - Related but not broader or narrower
Concept UI M000756166
Preferred term Complement 3 Glomerulopathies
Entry term(s) C3G Complement 3 Glomerulopathy
Complement 3 Glomerulopathy
Glomerulopathies, Complement 3
Glomerulopathy, Complement 3



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