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Descriptor English: Delta-5 Fatty Acid Desaturase
Descriptor Spanish: delta-5 Desaturasa de Ácido Graso
Descriptor delta-5-desaturasa de ácidos grasos
Entry term(s) delta-5-FADasa
delta-5-desaturasa
Scope note: Desaturasa de ácidos grasos que es una enzima limitante de la velocidad para la conversión de ácido dihomo-gamma-linolénico y eicosatetraenoato (ETA) en la síntesis de ÁCIDO ARAQUIDÓNICO y eicosapentaenoato (EPA). También interviene en la biosíntesis de ácidos grasos insaturados a partir de los precursores ácidos grasos poliinsaturados (AGPI), ÁCIDO LINOLEICO (AL) y ÁCIDO ALFA-LINOLÉNICO (AAL) y desempeña un papel importante en el metabolismo de los lípidos inflamatorios, incluida la PROSTAGLANDINA E2.
Descriptor Portuguese: Dessaturase de Ácido Graxo Delta-5
Descriptor French: Delta-5 fatty acid desaturase
Entry term(s): 5 Desaturase, Delta
Acid Delta-5-Desaturase, Fatty
Delta 5 Desaturase
Delta 5 FADase
Delta-5-Desaturase, Fatty Acid
Delta-5-FADase
Desaturase, Delta 5
Fatty Acid Delta 5 Desaturase
Fatty Acid Delta-5-Desaturase
Tree number(s): D08.811.682.690.708.392.390
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000090943
Scope note: A fatty acid desaturase that is a rate-limiting enzyme for the conversion from dihomo-gamma-linolenic acid and EICOSATETRAENOATE (ETA) in the synthesis of ARACHIDONIC ACID and EICOSAPENTAENOATE (EPA). It is also involved in the biosynthesis of unsaturated fatty acids from the polyunsaturated fatty acids (PUFA), LINOLEIC ACID (LA), and ALPHA LINOLENIC ACID (ALA) precursors and plays an important role in the metabolism of inflammatory lipids including PROSTAGLANDIN E2.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2022; DELTA-5 FATTY ACID DESATURASE was indexed under FATTY ACID DESATURASES 1982-2021
History Note: 2022 (1981)
DeCS ID: 59826
Unique ID: D000090943
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/06/28
Delta-5 Fatty Acid Desaturase - Preferred
Concept UI M000747567
Scope note A fatty acid desaturase that is a rate-limiting enzyme for the conversion from dihomo-gamma-linolenic acid and EICOSATETRAENOATE (ETA) in the synthesis of ARACHIDONIC ACID and EICOSAPENTAENOATE (EPA). It is also involved in the biosynthesis of unsaturated fatty acids from the polyunsaturated fatty acids (PUFA), LINOLEIC ACID (LA), and ALPHA LINOLENIC ACID (ALA) precursors and plays an important role in the metabolism of inflammatory lipids including PROSTAGLANDIN E2.
Preferred term Delta-5 Fatty Acid Desaturase
Entry term(s) 5 Desaturase, Delta
Acid Delta-5-Desaturase, Fatty
Delta 5 Desaturase
Delta 5 FADase
Delta-5-Desaturase, Fatty Acid
Delta-5-FADase
Desaturase, Delta 5
Fatty Acid Delta 5 Desaturase
Fatty Acid Delta-5-Desaturase



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