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Descriptor in English: Mixed Function Oxygenases
Descriptor in Spanish: Oxigenasas de Función Mixta
Descriptor in Portuguese: Oxigenases de Função Mista
Descriptor in French: Mixed function oxygenases
Entry term(s): Hydroxylases
Mixed Function Oxidases
Monooxygenases
Oxidases, Mixed Function
Oxygenases, Mixed Function
Tree number(s): D08.811.682.690.708
Scope note: Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
Annotation: do not confuse with HYDRO-LYASES
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 2003 (1966)
DeCS UI: 7067
Descriptor UI: D006899
Date Established: 2003/01/01
Date of Entry: 1999/01/01
Revision Date: 2004/07/07
Mixed Function Oxygenases - Preferred
Concept UI M0010768
Scope note Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
Preferred term Mixed Function Oxygenases
Entry term(s) Hydroxylases
Mixed Function Oxidases
Monooxygenases
Oxidases, Mixed Function
Oxygenases, Mixed Function



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