| Descriptor English: | Piwi-Interacting RNA | ||||||
| Descriptor Spanish: |
ARN de Interacción con Piwi
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| Descriptor Portuguese: | RNA de Interação com Piwi | ||||||
| Descriptor French: | ARN interagissant avec Piwi | ||||||
| Entry term(s): |
Piwi Interacting RNA RNA, Piwi Interacting RNA, Piwi-Interacting piRNA piRNAs |
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| Tree number(s): |
D13.150.650.700.500 D13.444.735.150.700.500 D13.444.735.790.552.875.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000094322 | ||||||
| Scope note: | A class of small RNAs that are 24–31 nucleotides in length. They associate with the PIWI SUBFAMILY OF ARGONAUTE PROTEINS to form effector complexes known as piRNA-induced silencing complexes, which repress transposons via transcriptional or posttranscriptional mechanisms and maintain germline genome integrity. In addition to their role in transposon silencing, piRNAs in diverse organisms function in the regulation of cellular genes. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
RNA, Small Interfering (2006-2022) |
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| Public MeSH Note: | 2023; see RNA,SMALL INTERFERING 2008-2022 |
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| History Note: | 2023; use RNA,SMALL INTERFERING 2008-2022 |
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| DeCS ID: | 60223 | ||||||
| Unique ID: | D000094322 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2023/01/01 | ||||||
| Date of Entry: | 2022/07/11 | ||||||
| Revision Date: | 2022/07/11 |
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Piwi-Interacting RNA
- Preferred
| Concept UI |
M0507094 |
| Scope note | A class of small RNAs that are 24–31 nucleotides in length. They associate with the PIWI SUBFAMILY OF ARGONAUTE PROTEINS to form effector complexes known as piRNA-induced silencing complexes, which repress transposons via transcriptional or posttranscriptional mechanisms and maintain germline genome integrity. In addition to their role in transposon silencing, piRNAs in diverse organisms function in the regulation of cellular genes. |
| Preferred term | Piwi-Interacting RNA |
| Entry term(s) |
Piwi Interacting RNA RNA, Piwi Interacting RNA, Piwi-Interacting piRNA piRNAs |
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