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Descriptor English: Gap Junction alpha-5 Protein
Descriptor Spanish: Proteína alfa-5 de Unión Comunicante
Descriptor proteína alfa-5 de la unión comunicante
Entry term(s) conexina 40
proteína A5 de la unión comunicante
proteína GJA5
proteína alfa 5 de la unión comunicante
proteína conexina 40
Scope note: Subunidad alfa de la UNIÓN COMUNICANTE que contiene cuatro dominios transmembrana que se expresa en el miocardio auricular y en el SISTEMA DE CONDUCCIÓN CARDÍACO ventricular, incluidas las FIBRAS DE PURKINJE. Las mutaciones en el gen humano GJA5 se asocian a anomalías de la conducción cardíaca, como la FIBRILACIÓN AURICULAR familiar.
Descriptor Portuguese: Proteína alfa-5 de Junções Comunicantes
Descriptor French: Without translation
Entry term(s): Connexin 40
Connexin 40 Protein
GJA5 Protein
Gap Junction A5
Gap Junction alpha 5 Protein
Gap Junction alpha5 Protein
Protein, Connexin 40
Protein, GJA5
Tree number(s): D12.776.543.585.250.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097003
Scope note: A GAP JUNCTION alpha subunit containing four transmembrane domains expressed in the atrial myocardium and ventricular HEART CONDUCTION SYSTEM including PURKINJE FIBERS. Mutations in the human gene GJA5 are associated with cardiac conduction abnormalities such as a familial ATRIAL FIBRILLATION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2024; see CONNEXINS 2010-2023
History Note: 2024(2010)
DeCS ID: 60544
Unique ID: D000097003
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/31
Gap Junction alpha-5 Protein - Preferred
Concept UI M000762846
Scope note A GAP JUNCTION alpha subunit containing four transmembrane domains expressed in the atrial myocardium and ventricular HEART CONDUCTION SYSTEM including PURKINJE FIBERS. Mutations in the human gene GJA5 are associated with cardiac conduction abnormalities such as a familial ATRIAL FIBRILLATION.
Preferred term Gap Junction alpha-5 Protein
Entry term(s) Connexin 40
Connexin 40 Protein
GJA5 Protein
Gap Junction A5
Gap Junction alpha 5 Protein
Gap Junction alpha5 Protein
Protein, Connexin 40
Protein, GJA5



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