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Descriptor English: Polo-Like Kinase 1
Descriptor Spanish: Quinasa Tipo Polo 1
Descriptor cinasa polo 1
Entry term(s) cinasa de tipo polo 1
cinasa tipo polo 1
proteína Plk1
proteína STPK13
Scope note: Cinasa que desempeña un papel esencial en la regulación de la actividad proliferativa de las células normales y malignas. Se ha propuesto como una nueva diana para las estrategias de tratamiento antineoplásico.
Descriptor Portuguese: Quinase 1 Polo-Like
Descriptor French: Without translation
Entry term(s): Plk1 protein
Polo Like Kinase 1
STPK13 protein
Tree number(s): D08.811.913.696.620.682.700.616.500
D12.776.476.563.616.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097869
Scope note: Plays a crucial role in the regulation of proliferative activity of normal and malignant cells. Proposed as a new target for antineoplastic treatment strategies.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2024
History Note: 2024
DeCS ID: 60688
Unique ID: D000097869
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/06/12
Polo-Like Kinase 1 - Preferred
Concept UI M000764652
Scope note Plays a crucial role in the regulation of proliferative activity of normal and malignant cells. Proposed as a new target for antineoplastic treatment strategies.
Preferred term Polo-Like Kinase 1
Entry term(s) Plk1 protein
Polo Like Kinase 1
STPK13 protein



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