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Descriptor English: Polo-like Kinases
Descriptor Spanish: Quinasas Tipo Polo
Descriptor cinasas polo
Entry term(s) cinasas de tipo polo
cinasas tipo polo
Scope note: Proteína-serina-treonina-cinasas que regulan la entrada en la fase M, la biogénesis y función de los polos del huso, la dinámica cromosómica mitótica, la salida mitótica y la citocinesis. Contienen un dominio de interacción proteínica polo-caja característico.
Descriptor Portuguese: Quinases Polo-Like
Descriptor French: Without translation
Tree number(s): D08.811.913.696.620.682.700.616
D12.776.167.469
D12.776.476.563.616
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097868
Scope note: Protein serine-threonine kinases which regulate entry into M phase, spindle pole biogenesis and function, mitotic chromosome dynamics, mitotic exit, and cytokinesis. They contain a characteristic Polo-box protein interaction domain.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Protein Serine-Threonine Kinases (1993-2023)
Public MeSH Note: 2024
History Note: 2024
DeCS ID: 60687
Unique ID: D000097868
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/06/12
Polo-like Kinases - Preferred
Concept UI M000764651
Scope note Protein serine-threonine kinases which regulate entry into M phase, spindle pole biogenesis and function, mitotic chromosome dynamics, mitotic exit, and cytokinesis. They contain a characteristic Polo-box protein interaction domain.
Preferred term Polo-like Kinases



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