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Descriptor English: Amitriptyline
Descriptor Spanish: Amitriptilina
Descriptor amitriptilina
Scope note: Antidepresivo tricíclico con propiedades anticolinérgicas y sedantes. Parece que previene la recaptación de noradrenalina y serotonina en las terminaciones nerviosas, potenciando de este modo la acción de estos neurotransmisores. También parece que la amitriptilina antagoniza las respuestas colinérgica y adrenérgica alfa-1 a las aminas bioactivas.
Descriptor Portuguese: Amitriptilina
Descriptor French: Amitriptyline
Entry term(s): Amineurin
Amitrip
Amitriptylin Beta
Amitriptylin Desitin
Amitriptylin Neuraxpharm
Amitriptylin RPh
Amitriptylin-Neuraxpharm
Amitriptyline Hydrochloride
Amitrol
Anapsique
Apo Amitriptyline
Apo-Amitriptyline
Damilen
Desitin, Amitriptylin
Domical
Elavil
Endep
Laroxyl
Lentizol
Novoprotect
RPh, Amitriptylin
Saroten
Sarotex
Syneudon
Triptafen
Tryptanol
Tryptine
Tryptizol
Tree number(s): D02.455.426.559.847.181.384.100
D04.615.181.384.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000639
Scope note: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antidepressive Agents, Tricyclic
Analgesics, Non-Narcotic
Adrenergic Uptake Inhibitors
Registry Number: 1806D8D52K
CAS Type 1 Name: 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-
Public MeSH Note: 64
History Note: 64(63)
DeCS ID: 652
Unique ID: D000639
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1964/01/01
Date of Entry: 1999/11/08
Revision Date: 2017/02/24
Amitriptyline - Preferred
Concept UI M0000975
Scope note Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
Preferred term Amitriptyline
Tryptine - Narrower
Concept UI M0433230
Preferred term Tryptine
Amineurin - Narrower
Concept UI M0433234
Preferred term Amineurin
Amitrip - Narrower
Concept UI M0433236
Preferred term Amitrip
Amitriptylin Beta - Narrower
Concept UI M0433251
Preferred term Amitriptylin Beta
Amitriptylin Desitin - Narrower
Concept UI M0433289
Preferred term Amitriptylin Desitin
Entry term(s) Desitin, Amitriptylin
Amitriptylin RPh - Narrower
Concept UI M0433290
Preferred term Amitriptylin RPh
Entry term(s) RPh, Amitriptylin
Amitriptylin-Neuraxpharm - Narrower
Concept UI M0433291
Preferred term Amitriptylin-Neuraxpharm
Entry term(s) Amitriptylin Neuraxpharm
Amitriptyline Hydrochloride - Narrower
Concept UI M0330766
Preferred term Amitriptyline Hydrochloride
Amitrol - Narrower
Concept UI M0433237
Preferred term Amitrol
Anapsique - Narrower
Concept UI M0433238
Preferred term Anapsique
Apo-Amitriptyline - Narrower
Concept UI M0433239
Preferred term Apo-Amitriptyline
Entry term(s) Apo Amitriptyline
Damilen - Narrower
Concept UI M0351387
Preferred term Damilen
Domical - Narrower
Concept UI M0433249
Preferred term Domical
Laroxyl - Narrower
Concept UI M0338111
Preferred term Laroxyl
Lentizol - Narrower
Concept UI M0000976
Preferred term Lentizol
Novoprotect - Narrower
Concept UI M0433233
Preferred term Novoprotect
Saroten - Narrower
Concept UI M0000977
Preferred term Saroten
Sarotex - Narrower
Concept UI M0433229
Preferred term Sarotex
Syneudon - Narrower
Concept UI M0433231
Preferred term Syneudon
Triptafen - Narrower
Concept UI M0433232
Preferred term Triptafen
Endep - Narrower
Concept UI M000613550
Preferred term Endep
Tryptizol - Narrower
Concept UI M0000978
Preferred term Tryptizol
Entry term(s) Elavil
Tryptanol



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