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Descriptor English: Intrinsic Factor
Descriptor Spanish: Factor Intrinseco
Descriptor factor intrínseco
Scope note: Glicoproteína segregada por las células de las glándulas gástricas y que es necesaria para la absorción de la VITAMINA B 12 (CIANOCOBALAMINA). El déficit de factor intrínseco provoca DÉFICIT DE VITAMINA B 12 y ANEMIA PERNICIOSA.
Descriptor Portuguese: Fator Intrínseco
Descriptor French: Facteur intrinsèque
Entry term(s): Factor, Intrinsic
Tree number(s): D09.400.430.900.494
D12.776.395.560.494
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007437
Scope note: A glycoprotein secreted by the cells of the GASTRIC GLANDS that is required for the absorption of VITAMIN B 12 (cyanocobalamin). Deficiency of intrinsic factor leads to VITAMIN B 12 DEFICIENCY and ANEMIA, PERNICIOUS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 9008-12-2
DeCS ID: 7599
Unique ID: D007437
NLM Classification: QU 195
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2009/08/03
Intrinsic Factor - Preferred
Concept UI M0011611
Scope note A glycoprotein secreted by the cells of the GASTRIC GLANDS that is required for the absorption of VITAMIN B 12 (cyanocobalamin). Deficiency of intrinsic factor leads to VITAMIN B 12 DEFICIENCY and ANEMIA, PERNICIOUS.
Preferred term Intrinsic Factor
Entry term(s) Factor, Intrinsic



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