| Descriptor English: | Maytansine | ||||||
| Descriptor Spanish: |
Maitansina
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| Descriptor Portuguese: | Maitansina | ||||||
| Descriptor French: | Maitansine | ||||||
| Entry term(s): |
DM1, Maytansinoid DM4, Maytansinoid DMMO Maytansine DMMO-Maytansine Emtansine Maitansine Maytansinoid DM1 Maytansinoid DM4 Mertansine N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine Ravtansine Soravtansine |
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| Tree number(s): |
D02.540.505.495 D04.345.295.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D008453 | ||||||
| Scope note: | An ansa macrolide isolated from the MAYTENUS genus of East African shrubs. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Antineoplastic Agents, Phytogenic Tubulin Modulators |
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| Registry Number: | 14083FR882 | ||||||
| Previous Indexing: |
Morpholines (1966-1975) Oxazines (1976) |
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| Public MeSH Note: | 91; was see under OXAZINES 1977-90 |
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| History Note: | 91(77); was see under OXAZINES 1977-90 |
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| DeCS ID: | 8621 | ||||||
| Unique ID: | D008453 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1976/05/03 | ||||||
| Revision Date: | 2018/07/02 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Polycyclic Compounds [D04]Polycyclic Compounds
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Maytansine
- Preferred
Maytansinoid DM1
- Related but not broader or narrower
Maytansinoid DM4
- Related but not broader or narrower
| Concept UI |
M0013148 |
| Scope note | An ansa macrolide isolated from the MAYTENUS genus of East African shrubs. |
| Preferred term | Maytansine |
| Entry term(s) |
Maitansine |
| Concept UI |
M000626530 |
| Preferred term | Maytansinoid DM1 |
| Entry term(s) |
DM1, Maytansinoid Emtansine Mertansine |
| Concept UI |
M000626532 |
| Preferred term | Maytansinoid DM4 |
| Entry term(s) |
DM4, Maytansinoid DMMO Maytansine DMMO-Maytansine N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine Ravtansine Soravtansine |
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