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Descriptor English: Meprobamate
Descriptor Spanish: Meprobamato
Descriptor meprobamato
Scope note: Carbamato con propiedades hipnóticas, sedantes y relajantes musculares, aunque en las dosis terapéuticas la reducción de la ansiedad más que un efecto directo puede ser responsable de la relajación muscular. Se ha descrito que el meprobamato tiene acciones anticonvulsionantes frente a las convulsiones del pequeño mal, pero no frente a las convulsiones del gran mal (que pueden estar exacerbadas). Se utiliza en el tratamiento de los TRASTORNOS DE ANSIEDAD, y también en el tratamiento a corto plazo del INSOMNIO pero ha quedado superado en gran medida por las BENZODIACEPINAS. (Martindale, The Extra Pharmacopoeia, 30th ed, p603)
Descriptor Portuguese: Meprobamato
Descriptor French: Méprobamate
Entry term(s): Dapaz
Equanil
Meprospan
Miltown
Méprobamate Richard
Tranmep
Visano
Tree number(s): D02.241.081.251.510
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008620
Scope note: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticonvulsants
Hypnotics and Sedatives
Muscle Relaxants, Central
Anti-Anxiety Agents
Registry Number: 9I7LNY769Q
CAS Type 1 Name: 1,3-Propanediol, 2-methyl-2-propyl-, dicarbamate
DeCS ID: 8792
Unique ID: D008620
NLM Classification: QV 77.9
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Meprobamate - Preferred
Concept UI M0013438
Scope note A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
Preferred term Meprobamate
Miltown - Narrower
Concept UI M0351493
Preferred term Miltown
Méprobamate Richard - Narrower
Concept UI M0473989
Preferred term Méprobamate Richard
Meprospan - Narrower
Concept UI M0473986
Preferred term Meprospan
Tranmep - Narrower
Concept UI M0473987
Preferred term Tranmep
Visano - Narrower
Concept UI M0473988
Preferred term Visano
Equanil - Narrower
Concept UI M0013439
Preferred term Equanil
Dapaz - Narrower
Concept UI M0473985
Preferred term Dapaz



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