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Descriptor English: Darunavir
Descriptor Spanish: Darunavir
Descriptor darunavir
Scope note: Un INHIBIDOR DE LA PROTEASA VIH que se utiliza en el tratamiento del SIDA y las INFECCIONES POR VIH. Debido a la aparición de la FARMACORRESISTENCIA VIRAL cuando se utiliza solo, se administra en combinación con otros AGENTES ANTI VIH.
Descriptor Portuguese: Darunavir
Descriptor French: Darunavir
Entry term(s): 114, TMC
Darunavir Ethanolate
Ethanolate, Darunavir
Prezista
TMC 114
TMC-114
TMC114
UIC 94017
UIC-94017
UIC94017
Tree number(s): D02.065.884.438
D02.241.081.251.222
D02.886.590.700.400
D03.383.312.303
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069454
Scope note: An HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: HIV Protease Inhibitors
Registry Number: YO603Y8113
CAS Type 1 Name: (3-((4-aminobenzenesulfonyl)isobutylamino)-1-benzyl-2-hydroxypropyl)carbamic acid hexahydrofuro(2,3-b)furan-3-yl ester
Public MeSH Note: 2016; DARUNAVIR was indexed under SULFONAMIDES 2004-2015
History Note: 2016 (2004)
DeCS ID: 55875
Unique ID: D000069454
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/28
Darunavir - Preferred
Concept UI M0461844
Scope note An HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS.
Preferred term Darunavir
Prezista - Narrower
Concept UI M0499324
Preferred term Prezista
UIC-94017 - Narrower
Concept UI M0499322
Preferred term UIC-94017
Entry term(s) UIC 94017
UIC94017
Darunavir Ethanolate - Narrower
Concept UI M0501231
Preferred term Darunavir Ethanolate
Entry term(s) Ethanolate, Darunavir
TMC 114 - Narrower
Concept UI M0480520
Preferred term TMC 114
Entry term(s) 114, TMC
TMC-114
TMC114



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