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Descriptor English: Neuritis, Autoimmune, Experimental
Descriptor Spanish: Neuritis Autoinmune Experimental
Descriptor neuritis autoinmune experimental
Entry term(s) neuritis alérgica experimental
neuritis experimental alérgica
neuritis experimental autoinmune
Scope note: Modelo experimental animal de la enfermedad desmielinizante del SÍNDROME DE GUILLAINE-BARRE. En el protocolo utilizado con mayor frecuencia se inyecta a los animales un homogeneizado proteico de tejido nervioso periférico. Al cabo de unas 2 semanas, se desarrolla en los animales una neuropatía secundaria a una respuesta autoinmunitaria mediada por células T dirigida contra la PROTEÍNA P2 DE LA MIELINA en los nervios periféricos. Los hallazgos anatomopatológicos consisten en acúmulos perivasculares de macrófagos y linfocitos T en el sistema nervioso periférico, similares a los que se observan en el síndrome de Guillaine-Barré. (Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)
Descriptor Portuguese: Neurite Autoimune Experimental
Descriptor French: Névrite auto-immune expérimentale
Entry term(s): Allergic Neuritis, Experimental
Autoimmune Neuritis, Experimental
Autoimmune Neuropathies, Experimental
Autoimmune Neuropathy, Experimental
EAN (Experimental Allergic Neuritis)
EAN (Experimental Autoimmune Neuritis)
Experimental Allergic Neuritis
Experimental Autoimmune Neuritis
Experimental Autoimmune Neuropathies
Experimental Autoimmune Neuropathy
Neuritis, Experimental Allergic
Neuritis, Experimental Autoimmune
Neuropathies, Experimental Autoimmune
Neuropathy, Experimental Autoimmune
Tree number(s): C10.114.703.700
C10.668.829.650.500
C20.111.258.625.700
E05.598.500.500.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009444
Scope note: An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)
Annotation: coordinate with GUILLAINE-BARRE SYNDROME if pertinent
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Myelin Sheath (1966-1981)
Neuritis (1966-1981)
Peripheral Nerves (1966-1981)
Public MeSH Note: 2005; see NEURITIS, EXPERIMENTAL ALLERGIC 1982-2004
History Note: 2005 (1982)
Entry Version: NEURITIS AUTOIMMUNE EXPER
DeCS ID: 9637
Unique ID: D009444
NLM Classification: WL 544
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1982/01/01
Date of Entry: 1981/02/23
Revision Date: 2004/07/07
Neuritis, Autoimmune, Experimental - Preferred
Concept UI M0014694
Scope note An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)
Preferred term Neuritis, Autoimmune, Experimental
Entry term(s) Allergic Neuritis, Experimental
Autoimmune Neuritis, Experimental
Autoimmune Neuropathies, Experimental
Autoimmune Neuropathy, Experimental
EAN (Experimental Allergic Neuritis)
EAN (Experimental Autoimmune Neuritis)
Experimental Allergic Neuritis
Experimental Autoimmune Neuritis
Experimental Autoimmune Neuropathies
Experimental Autoimmune Neuropathy
Neuritis, Experimental Allergic
Neuritis, Experimental Autoimmune
Neuropathies, Experimental Autoimmune
Neuropathy, Experimental Autoimmune



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