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Descriptor English: Nitracrine
Descriptor Spanish: Nitracrina
Descriptor nitracrina
Entry term(s) C-283
Scope note: Agente antineoplásico acridínico utilizado en tumores de mama y ovarios. Inhibe la síntesis de ARN.
Descriptor Portuguese: Nitracrina
Descriptor French: Nitracrine
Entry term(s): C 283
C-283
C283
Ledakrin
Tree number(s): D03.633.300.046.250.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009564
Scope note: Acridine antineoplastic agent used in mammary and ovarian tumors. It inhibits RNA synthesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Nucleic Acid Synthesis Inhibitors
Registry Number: 712MLZ30SB
CAS Type 1 Name: 1,3-Propanediamine, N,N-dimethyl-N'-(1-nitro-9-acridinyl)-
Previous Indexing: Acridines (1971-1974)
Dimethylamines (1973-1974)
Nitro Compounds (1972-1974)
Public MeSH Note: 91; was see under AMINOACRIDINES 1985-90; was C 283 see under AMINOACRIDINES 1981-84; was C 283 see under ACRIDINES 1975-80
Online Note: use NITRACRINE to search C 283 1975-84
History Note: 91(85); was see under AMINOACRIDINES 1985-90; was C 283 see under AMINOACRIDINES 1981-84; was C 283 see under ACRIDINES 1975-80
DeCS ID: 9749
Unique ID: D009564
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Nitracrine - Preferred
Concept UI M0014872
Scope note Acridine antineoplastic agent used in mammary and ovarian tumors. It inhibits RNA synthesis.
Preferred term Nitracrine
Ledakrin - Narrower
Concept UI M0373115
Preferred term Ledakrin
C-283 - Narrower
Concept UI M0014871
Preferred term C-283
Entry term(s) C 283
C283



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