| Descriptor English: | 4-Nitroquinoline-1-oxide | ||||||
| Descriptor Spanish: |
4-Nitroquinolina-1-Óxido
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| Descriptor Portuguese: | 4-Nitroquinolina-1-Óxido | ||||||
| Descriptor French: | 4-Nitro-quinoléine-1-oxyde | ||||||
| Entry term(s): |
4 Nitroquinoline 1 oxide 4 Nitroquinoline N oxide 4-Nitroquinoline-N-oxide |
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| Tree number(s): |
D02.640.820.600 D03.633.100.810.470.450 D03.661.243.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015112 | ||||||
| Scope note: | A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AN analysis CH chemistry CL classification CS chemical synthesis EC economics HI history IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use |
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| Pharm Action: |
Carcinogens Mutagens |
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| Registry Number: | 56-57-5 | ||||||
| CAS Type 1 Name: | Quinoline, 4-nitro-, 1-oxide | ||||||
| Previous Indexing: |
Cyclic N-Oxides (1972-1974) Nitro Compounds (1972-1974) Quinolines (1970-1974) |
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| Public MeSH Note: | 91; was see under NITROQUINOLINES 1975-90 |
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| History Note: | 91(75); was see under NITROQUINOLINES 1975-90 |
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| DeCS ID: | 9786 | ||||||
| Unique ID: | D015112 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1974/11/14 | ||||||
| Revision Date: | 2016/05/27 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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4-Nitroquinoline-1-oxide
- Preferred
| Concept UI |
M0023243 |
| Scope note | A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage. |
| Preferred term | 4-Nitroquinoline-1-oxide |
| Entry term(s) |
4 Nitroquinoline 1 oxide 4 Nitroquinoline N oxide 4-Nitroquinoline-N-oxide |
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