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Descriptor in English: Nucleic Acid Heteroduplexes
Descriptor in Spanish: Ácidos Nucleicos Heterodúplex
Descriptor in Portuguese: Ácidos Nucleicos Heteroduplexes
Descriptor in French: Hétéroduplexes d'acides nucléiques
Entry term(s): Acid Heteroduplexes, Nucleic
DNA, Heteroduplex
Heteroduplex DNA
Heteroduplexes, Nucleic Acid
Tree number(s): D13.444.500
Scope note: Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
Annotation: coord with specific DNA or RNA or both (IM)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 80
See also the descriptors: Base Pair Mismatch MeSH
Heteroduplex Analysis MeSH
DeCS UI: 9879
Descriptor UI: D009692
Date Established: 1980/01/01
Date of Entry: 1979/05/23
Revision Date: 1998/06/10
Nucleic Acid Heteroduplexes - Preferred
Concept UI M0015051
Scope note Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
Preferred term Nucleic Acid Heteroduplexes
Entry term(s) Acid Heteroduplexes, Nucleic
Heteroduplexes, Nucleic Acid
Heteroduplex DNA - Narrower
Concept UI M0015050
Preferred term Heteroduplex DNA
Entry term(s) DNA, Heteroduplex



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