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Descriptor English: Nucleic Acid Heteroduplexes
Descriptor Spanish: Ácidos Nucleicos Heterodúplex
Descriptor heterodúplex de ácidos nucleicos
Scope note: Moléculas de ácidos nucleicos bicatenarios (ADN-ADN o ADN-ARN) que contienen regiones de malapareamiento de nucleótidos (no complementarios). In vivo, estos heterodúplex pueden producirse por mutación o recombinación genética; in vitro, se forman por hibridación de ácidos nucleicos. El análisis por microscopía electrónica de los heterodúplex resultantes facilita el mapeo de regiones de similitud (homología) de secuencias de bases de ácidos nucleicos.
Descriptor Portuguese: Ácidos Nucleicos Heteroduplexes
Descriptor French: Hétéroduplexes d'acides nucléiques
Entry term(s): Acid Heteroduplexes, Nucleic
DNA, Heteroduplex
Heteroduplex DNA
Heteroduplexes, Nucleic Acid
Tree number(s): D13.444.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009692
Scope note: Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
Annotation: coord with specific DNA or RNA or both (IM)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Base Sequence (1971-1979)
DNA (1966-1979)
Mutation (1966-1979)
Nucleic Acid Hybridization (1971-1979)
RNA (1966-1979)
Recombination, Genetic (1968-1979)
specific DNA (1966-1979)
specific RNA (1966-1979)
Public MeSH Note: 80
History Note: 80
Related: Base Pair Mismatch MeSH
Heteroduplex Analysis MeSH
DeCS ID: 9879
Unique ID: D009692
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1979/05/23
Revision Date: 1998/06/10
Nucleic Acid Heteroduplexes - Preferred
Concept UI M0015051
Scope note Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
Preferred term Nucleic Acid Heteroduplexes
Entry term(s) Acid Heteroduplexes, Nucleic
Heteroduplexes, Nucleic Acid
Heteroduplex DNA - Narrower
Concept UI M0015050
Preferred term Heteroduplex DNA
Entry term(s) DNA, Heteroduplex



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