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Descriptor English: Pepsinogens
Descriptor Spanish: Pepsinógenos
Descriptor Portuguese: Pepsinogênios
Descriptor French: Pepsinogènes
Entry term(s): Pepsinogen B
Tree number(s): D08.622.509
D12.776.811.243.509
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010435
Scope note: Proenzymes secreted by chief cells, mucous neck cells, and pyloric gland cells, which are converted into pepsin in the presence of gastric acid or pepsin itself. (Dorland, 28th ed) In humans there are 2 related pepsinogen systems: PEPSINOGEN A (formerly pepsinogen I or pepsinogen) and PEPSINOGEN C (formerly pepsinogen II or progastricsin). Pepsinogen B is the name of a pepsinogen from pigs.
Annotation: do not confuse with PEPSINOGEN see PEPSINOGEN A
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Enzyme Precursors (1966-1971)
Pepsin (1966-1971)
Pepsinogen (1972-1998)
Public MeSH Note: 99; see Pepsinogen 1972-98
History Note: 99(72)
Related: Gastric Juice MeSH
DeCS ID: 10630
Unique ID: D010435
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1972/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/23
Pepsinogens - Preferred
Concept UI M0016207
Scope note Proenzymes secreted by chief cells, mucous neck cells, and pyloric gland cells, which are converted into pepsin in the presence of gastric acid or pepsin itself. (Dorland, 28th ed) In humans there are 2 related pepsinogen systems: PEPSINOGEN A (formerly pepsinogen I or pepsinogen) and PEPSINOGEN C (formerly pepsinogen II or progastricsin). Pepsinogen B is the name of a pepsinogen from pigs.
Preferred term Pepsinogens
Pepsinogen B - Narrower
Concept UI M0016208
Preferred term Pepsinogen B



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