| Descriptor English: | Protein C | ||||
| Descriptor Spanish: |
Proteína C
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| Descriptor Portuguese: | Proteína C | ||||
| Descriptor French: | Protéine C | ||||
| Tree number(s): |
D08.622.705 D12.776.124.650 D12.776.395.635 D12.776.811.243.705 D23.113.700 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011486 | ||||
| Scope note: | A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
deficiency:Protein C Deficiency
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| Pharm Action: |
Anticoagulants Fibrinolytic Agents |
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| Previous Indexing: |
Blood Proteins (1966-1986) Glycoproteins (1966-1986) |
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| Public MeSH Note: | 87 |
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| History Note: | 87 |
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| DeCS ID: | 22311 | ||||
| Unique ID: | D011486 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1987/01/01 | ||||
| Date of Entry: | 1986/06/02 | ||||
| Revision Date: | 2005/06/30 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Protein C
- Preferred
| Concept UI |
M0017852 |
| Scope note | A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation. |
| Preferred term | Protein C |
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