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Descriptor English: Peptide Chain Initiation, Translational
Descriptor Spanish: Iniciación de la Cadena Peptídica Traduccional
Descriptor iniciación de la cadena peptídica de la traducción
Entry term(s) iniciación de la cadena peptídica en la traducción
iniciación de la traducción de proteínas
iniciación traduccional
iniciación traduccional de la cadena peptídica
Scope note: Proceso de TRADUCCIÓN GENÉTICA en el que se inicia la formación de una cadena peptídica. Incluye la reunión de los componentes de los RIBOSOMAS, la codificación del ARN MENSAJERO para que se produzca el polipéptido, ARNT INICIADOR, FACTORES DE INICIACIÓN DE PÉPTIDOS y colocación del primer aminoácido en la cadena peptídica. Los detalles y componentes de este proceso son únicos en la biosíntesis de las proteínas procariotas y eucariotas.
Descriptor Portuguese: Iniciação Traducional da Cadeia Peptídica
Descriptor French: Initiation de la traduction
Entry term(s): Biosynthesis Initiation, Protein
Chain Initiation, Peptide, Translational
Genetic Translation Initiation
Initiation, Genetic Translation
Initiation, Protein Biosynthesis
Initiation, Protein Translation
Initiation, Protein Translational
Protein Biosynthesis Initiation
Protein Chain Initiation, Translational
Protein Translation Initiation
Protein Translational Initiation
Translation Initiation, Genetic
Translation Initiation, Protein
Translational Initiation, Protein
Translational Peptide Chain Initiation
Tree number(s): G02.111.660.871.650
G03.734.871.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010442
Scope note: A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started. It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement of the first amino acid in the peptide chain. The details and components of this process are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis.
Annotation: coordinate with specific peptide; for protein biosynthesis on the ribosome only; for non-ribosomal biosynthesis use PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Peptides/biosynthesis (1966-1970)
Public MeSH Note: 2005; see PEPTIDE CHAIN INITIATION 1973-2004
History Note: 73(71)
Related: Codon, Initiator MeSH
Peptide Initiation Factors MeSH
Protein Synthesis Inhibitors MeSH
DeCS ID: 10638
Unique ID: D010442
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Peptide Chain Initiation, Translational - Preferred
Concept UI M0016216
Scope note A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started. It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement of the first amino acid in the peptide chain. The details and components of this process are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis.
Preferred term Peptide Chain Initiation, Translational
Entry term(s) Biosynthesis Initiation, Protein
Chain Initiation, Peptide, Translational
Genetic Translation Initiation
Initiation, Genetic Translation
Initiation, Protein Biosynthesis
Initiation, Protein Translation
Initiation, Protein Translational
Protein Biosynthesis Initiation
Protein Chain Initiation, Translational
Protein Translation Initiation
Protein Translational Initiation
Translation Initiation, Genetic
Translation Initiation, Protein
Translational Initiation, Protein
Translational Peptide Chain Initiation



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