| Descriptor English: | Phenylethanolamine N-Methyltransferase | ||||||
| Descriptor Spanish: |
Feniletanolamina N-Metiltransferasa
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| Descriptor Portuguese: | Feniletanolamina N-Metiltransferase | ||||||
| Descriptor French: | Phenylethanolamine n-methyltransferase | ||||||
| Entry term(s): |
Methyltransferase, Norepinephrine Noradrenalin N Methyltransferase Noradrenalin N-Methyltransferase Noradrenaline N Methyltransferase Noradrenaline N-Methyltransferase Norepinephrine Methyltransferase Norepinephrine N Methyltransferase Norepinephrine N-Methyltransferase Phenethanolamine N Methyltransferase Phenethanolamine N-Methyltransferase Phenylethanolamine N Methyltransferase |
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| Tree number(s): |
D08.811.913.555.500.700 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D010625 | ||||||
| Scope note: | A methyltransferase that catalyzes the reaction of S-adenosyl-L-methionine and phenylethanolamine to yield S-adenosyl-L-homocysteine and N-methylphenylethanolamine. It can act on various phenylethanolamines and converts norepinephrine into epinephrine. (From Enzyme Nomenclature, 1992) EC 2.1.1.28. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.1.1.28 | ||||||
| CAS Type 1 Name: | S-Adenosyl-L-methionine:phenylethanolamine N-methyltransferase | ||||||
| Previous Indexing: |
Methyltransferases (1971) Transferases (1966-1971) |
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| Public MeSH Note: | 74 |
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| History Note: | 74(72) |
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| DeCS ID: | 10816 | ||||||
| Unique ID: | D010625 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1974/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2003/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Phenylethanolamine N-Methyltransferase
- Preferred
| Concept UI |
M0016504 |
| Scope note | A methyltransferase that catalyzes the reaction of S-adenosyl-L-methionine and phenylethanolamine to yield S-adenosyl-L-homocysteine and N-methylphenylethanolamine. It can act on various phenylethanolamines and converts norepinephrine into epinephrine. (From Enzyme Nomenclature, 1992) EC 2.1.1.28. |
| Preferred term | Phenylethanolamine N-Methyltransferase |
| Entry term(s) |
Methyltransferase, Norepinephrine Noradrenalin N Methyltransferase Noradrenalin N-Methyltransferase Noradrenaline N Methyltransferase Noradrenaline N-Methyltransferase Norepinephrine Methyltransferase Norepinephrine N Methyltransferase Norepinephrine N-Methyltransferase Phenethanolamine N Methyltransferase Phenethanolamine N-Methyltransferase Phenylethanolamine N Methyltransferase |
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