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Descriptor English: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Descriptor Spanish: 5-Metiltetrahidrofolato-Homocisteína S-Metiltransferasa
Descriptor 5-metiltetrahidrofolato-homocisteína S-metiltransferasa
Entry term(s) metiltetrahidrofolato-homocisteína metiltransferasa
metionina sintetasa
tetrahidropteroilglutamato metiltransferasa
Scope note: Enzima que cataliza la formación de metionina mediante transferencia de un grupo metilo del 5-metiltetrahidrofolato a la homocisteína. Requiere una coenzima cobamida. La enzima puede actuar sobre derivados de mono o triglutamato. Ec 2.1.1.13.
Descriptor Portuguese: 5-Metiltetra-Hidrofolato-Homocisteína S-Metiltransferase
Descriptor French: 5-Methyltetrahydrofolate-homocysteine s-methyltransferase
Entry term(s): Homocysteine Methyltransferase, Methyltetrahydrofolate
Methionine Synthase
Methionine Synthetase
Methyltetrahydrofolate Homocysteine Methyltransferase
Methyltransferase, Methyltetrahydrofolate Homocysteine
Methyltransferase, Tetrahydropteroylglutamate
S-Methyltransferase, 5-Methyltetrahydrofolate-Homocysteine
Synthase, Methionine
Synthetase, Methionine
Tetrahydropteroylglutamate Methyltransferase
Vitamin B12-Dependent Methionine Synthase
Vitamin B12-Independent Methionine Synthase
Tree number(s): D08.811.913.555.500.645
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013766
Scope note: An enzyme that catalyzes the formation of methionine by transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine. It requires a cobamide coenzyme. The enzyme can act on mono- or triglutamate derivatives. EC 2.1.1.13.
Annotation: /defic: consider also HOMOCYSTINURIA; DF: note short X ref
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.1.1.13
CAS Type 1 Name: 5-Methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase
Previous Indexing: Methionine (1973-1974)
Methyltransferases (1973-1974)
Tetrahydrofolates (1973-1974)
Public MeSH Note: 98; see TETRAHYDROPTEROYLGLUTAMATE METHYLTRANSFERASE 1991-97; see METHYLTRANSFERASES 1975-90
History Note: 98(75)
Related: Homocystinuria MeSH
DeCS ID: 14145
Unique ID: D013766
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2005/06/30
5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase - Preferred
Concept UI M0021236
Scope note An enzyme that catalyzes the formation of methionine by transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine. It requires a cobamide coenzyme. The enzyme can act on mono- or triglutamate derivatives. EC 2.1.1.13.
Preferred term 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Entry term(s) Homocysteine Methyltransferase, Methyltetrahydrofolate
Methionine Synthase
Methionine Synthetase
Methyltetrahydrofolate Homocysteine Methyltransferase
Methyltransferase, Methyltetrahydrofolate Homocysteine
Methyltransferase, Tetrahydropteroylglutamate
S-Methyltransferase, 5-Methyltetrahydrofolate-Homocysteine
Synthase, Methionine
Synthetase, Methionine
Tetrahydropteroylglutamate Methyltransferase
Vitamin B12-Independent Methionine Synthase - Narrower
Concept UI M0021238
Preferred term Vitamin B12-Independent Methionine Synthase
Vitamin B12-Dependent Methionine Synthase - Narrower
Concept UI M0021237
Preferred term Vitamin B12-Dependent Methionine Synthase



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