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Descriptor in English: Pimozide
Descriptor in Spanish: Pimozida
Descriptor in Portuguese: Pimozida
Descriptor in French: Pimozide
Entry term(s): Antalon
Orap
Orap forte
R-6238
R6238
Tree number(s): D03.633.100.103.732
Scope note: A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 73
DeCS UI: 11301
Descriptor UI: D010868
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Pimozide - Preferred
Concept UI M0016871
Scope note A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
Preferred term Pimozide
Antalon - Narrower
Concept UI M0474773
Preferred term Antalon
Orap - Narrower
Concept UI M0474774
Preferred term Orap
Entry term(s) Orap forte
R-6238 - Narrower
Concept UI M0353569
Preferred term R-6238
Entry term(s) R6238



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