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Descriptor English: Dabigatran
Descriptor Spanish: Dabigatrán
Descriptor dabigatrán
Scope note: Inhibidor de la TROMBINA que actúa mediante la unión y bloqueo de la actividad trombogénica y en la prevención de la formación de trombos. Se utiliza para reducir el riesgo de accidente cerebrovascular y EMBOLIA sistémica en pacientes con fibrilación auricular no valvular.
Descriptor Portuguese: Dabigatrana
Descriptor French: Dabigatran
Entry term(s): BIBR 1048
Dabigatran Etexilate
Dabigatran Etexilate Mesylate
Etexilate Mesylate, Dabigatran
Etexilate, Dabigatran
Mesylate, Dabigatran Etexilate
N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine
Pradaxa
Tree number(s): D03.383.725.192
D03.633.100.103.280
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069604
Scope note: A THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antithrombins
Registry Number: I0VM4M70GC
Public MeSH Note: 2016; DABIGATRAN was indexed under BENZIMIDOAZOLES and BETA-ALANINE 2010-2015; DABIGATRAN ETEXILATE was indexed under BENZIMIDOAZOLES and PYRIDINES 2002-2015
History Note: 2016 (2002)
DeCS ID: 55927
Unique ID: D000069604
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/10
Revision Date: 2016/05/28
Dabigatran - Preferred
Concept UI M0553211
Scope note A THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.
Preferred term Dabigatran
Entry term(s) N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine
BIBR 1048 - Narrower
Concept UI M0486089
Preferred term BIBR 1048
Pradaxa - Narrower
Concept UI M0555256
Preferred term Pradaxa
Dabigatran Etexilate - Narrower
Concept UI M0423372
Preferred term Dabigatran Etexilate
Entry term(s) Etexilate, Dabigatran
Dabigatran Etexilate Mesylate - Narrower
Concept UI M0557657
Preferred term Dabigatran Etexilate Mesylate
Entry term(s) Etexilate Mesylate, Dabigatran
Mesylate, Dabigatran Etexilate



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