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Descriptor in English: Bisbenzimidazole
Descriptor in Spanish: Bisbenzimidazol
Descriptor in Portuguese: Bisbenzimidazol
Descriptor in French: Bisbenzimide
Entry term(s): 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride
Bisbenzimidazole Trihydrochloride
Bisbenzimide
Hoe 33258
Hoe-33258
Hoe33258
Hoechst 33258
NSC 322921
NSC-322921
NSC322921
Pibenzimol
Tree number(s): D03.633.100.103.145
Scope note: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2008(1977)
DeCS UI: 6845
Descriptor UI: D006690
Date Established: 1991/01/01
Date of Entry: 1976/04/13
Revision Date: 2016/05/27
Bisbenzimidazole - Preferred
Concept UI M0515726
Scope note A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Preferred term Bisbenzimidazole
Entry term(s) Pibenzimol
NSC-322921 - Narrower
Concept UI M0353557
Preferred term NSC-322921
Entry term(s) NSC 322921
NSC322921
Bisbenzimidazole Trihydrochloride - Narrower
Concept UI M0010486
Preferred term Bisbenzimidazole Trihydrochloride
Entry term(s) 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride
Bisbenzimide
Hoechst 33258 - Narrower
Concept UI M0353558
Preferred term Hoechst 33258
Entry term(s) Hoe 33258
Hoe-33258
Hoe33258



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