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Descriptor English: Quinone Reductases
Descriptor Spanish: Quinona Reductasas
Descriptor quinona reductasas
Scope note: NAD(P)H:(aceptor de quinona) oxidoredutasas. Familia que icomprende tres enzimas que se distinguen por su sensibilidad a varios inhibidores. EC 1.6.99.2.(NAD(P)H DESHIDROGENASA(QUINONA) es una flavoproteína que reduce diversas quinonas en presencia de NADH o NADPH y es inhibida por el dicumarol. EC 1.6.99.5 (NADH deshidrogenasa (quinona)) requiere NADH, es inhibida por AMP y 2,4-dinitrofenol, pero no por el dicumarol o derivados del ácido fólico. EC 1.6.99.6 (NADPH deshidrogenasa (quinona) requiere NADPH y es inhibida por el dicumarol y por derivados del ácido fólico, pero no por 2,4-dinitrofenol.
Descriptor Portuguese: Quinona Redutases
Descriptor French: Quinone reductases
Entry term(s): Menaquinone Reductases
Reductases, Menaquinone
Reductases, Quinone
Tree number(s): D08.811.682.608.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011808
Scope note: NAD(P)H:(quinone acceptor) oxidoreductases. A family that includes three enzymes which are distinguished by their sensitivity to various inhibitors. EC 1.6.99.2 (NAD(P)H DEHYDROGENASE (QUINONE);) is a flavoprotein which reduces various quinones in the presence of NADH or NADPH and is inhibited by dicoumarol. EC 1.6.99.5 (NADH dehydrogenase (quinone)) requires NADH, is inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. EC 1.6.99.6 (NADPH dehydrogenase (quinone)) requires NADPH and is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.6.99.-
Previous Indexing: NADH, NADPH Oxidoreductases (1973-1974)
Vitamin K (1973-1974)
Public MeSH Note: 86; was see under NADH, NADPH OXIDOREDUCTASES 1975-85
History Note: 86(75); was see under NADH, NADPH OXIDOREDUCTASES 1975-85
DeCS ID: 12245
Unique ID: D011808
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1974/11/19
Revision Date: 2006/07/05
Quinone Reductases - Preferred
Concept UI M0018355
Scope note NAD(P)H:(quinone acceptor) oxidoreductases. A family that includes three enzymes which are distinguished by their sensitivity to various inhibitors. EC 1.6.99.2 (NAD(P)H DEHYDROGENASE (QUINONE);) is a flavoprotein which reduces various quinones in the presence of NADH or NADPH and is inhibited by dicoumarol. EC 1.6.99.5 (NADH dehydrogenase (quinone)) requires NADH, is inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. EC 1.6.99.6 (NADPH dehydrogenase (quinone)) requires NADPH and is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol.
Preferred term Quinone Reductases
Entry term(s) Reductases, Quinone
Menaquinone Reductases - Narrower
Concept UI M0018354
Preferred term Menaquinone Reductases
Entry term(s) Reductases, Menaquinone



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