| Descriptor English: | Electron Transport Complex I | ||||||
| Descriptor Spanish: |
Complejo I de Transporte de Electrón
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| Descriptor Portuguese: | Complexo I de Transporte de Elétrons | ||||||
| Descriptor French: | Complexe I de la chaîne respiratoire | ||||||
| Entry term(s): |
Complex I Dehydrogenase Dehydrogenase, Complex I NADH CoQ Reductase NADH Coenzyme Q Reductase NADH DH I NADH Dehydrogenase (Ubiquinone) NADH Dehydrogenase Complex 1 NADH Dehydrogenase I NADH Q1 Oxidoreductase NADH Ubiquinone Oxidoreductase NADH Ubiquinone Reductase NADH-CoQ Reductase NADH-Coenzyme Q Reductase NADH-Ubiquinone Oxidoreductase NADH-Ubiquinone Reductase Oxidoreductase, NADH Q1 Oxidoreductase, NADH-Ubiquinone Reductase, NADH-Ubiquinone Respiratory Complex I Rotenone Sensitive Mitochondrial NADH Ubiquinone Oxidoreductase Rotenone-Sensitive Mitochondrial NADH-Ubiquinone Oxidoreductase Ubiquinone Reductase |
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| Tree number(s): |
D05.500.562.249 D08.811.600.250.500.500 D08.811.682.608.504 D12.776.157.427.374.375.863 D12.776.157.530.450.250.875.300 D12.776.331.199.500 D12.776.543.277.500.500 D12.776.543.585.450.250.875.437 D12.776.556.579.374.375.140 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D042967 | ||||||
| Scope note: | A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UBIQUINONE to ubiquinol. In MITOCHONDRIA the complex also couples its reaction to the transport of PROTONS across the internal mitochondrial membrane. The NADH DEHYDROGENASE component of the complex can be isolated and is listed as EC 1.6.99.3. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 1.6.5.3 | ||||||
| Previous Indexing: |
Cytochrome Reductases (1983-2003) NADH, NADPH Oxidoreductases (1992-2003) |
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| Public MeSH Note: | 2004; NADH DEHYDROGENASE (UBIQUINONE) was indexed under NADH, NADPH OXIDOREDUCTASES 1992-2003; for NADH DEHYDROGENASE use NADH DEHYDROGENASE 1990-2003; for UBIQUINONE REDUCTASE see NAD(P)H DEHYDROGENASE (QUINONE) 1992-1999 |
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| History Note: | 2004; for NADH DEHYDROGENASE (UBIQUINONE) use ELECTRON TRANSPORT COMPLEX I (NM) 1992-2003; for NADH DEHYDROGENASE COMPLEX 1 use NADH DEHYDROGENASE 1989-2003; for UBIQUINONE REDUCTASE use NAD(P)H DEHYDROGENASE (QUINONE) 1992-1999 |
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| DeCS ID: | 38189 | ||||||
| Unique ID: | D042967 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2004/01/01 | ||||||
| Date of Entry: | 2003/07/09 | ||||||
| Revision Date: | 2011/06/24 |
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CHEMICALS AND DRUGS
Macromolecular Substances [D05]Macromolecular Substances -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Electron Transport Complex I
- Preferred
NADH Dehydrogenase (Ubiquinone)
- Narrower
| Concept UI |
M0205105 |
| Scope note | A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UBIQUINONE to ubiquinol. In MITOCHONDRIA the complex also couples its reaction to the transport of PROTONS across the internal mitochondrial membrane. The NADH DEHYDROGENASE component of the complex can be isolated and is listed as EC 1.6.99.3. |
| Preferred term | Electron Transport Complex I |
| Entry term(s) |
Respiratory Complex I |
| Concept UI |
M0447491 |
| Preferred term | NADH Dehydrogenase (Ubiquinone) |
| Entry term(s) |
Complex I Dehydrogenase Dehydrogenase, Complex I NADH CoQ Reductase NADH Coenzyme Q Reductase NADH DH I NADH Dehydrogenase Complex 1 NADH Dehydrogenase I NADH Q1 Oxidoreductase NADH Ubiquinone Oxidoreductase NADH Ubiquinone Reductase NADH-CoQ Reductase NADH-Coenzyme Q Reductase NADH-Ubiquinone Oxidoreductase NADH-Ubiquinone Reductase Oxidoreductase, NADH Q1 Oxidoreductase, NADH-Ubiquinone Reductase, NADH-Ubiquinone Rotenone Sensitive Mitochondrial NADH Ubiquinone Oxidoreductase Rotenone-Sensitive Mitochondrial NADH-Ubiquinone Oxidoreductase Ubiquinone Reductase |
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